- Bone Marrow Transplant
- Enzyme Replacement Therapy
Alpha Mannosidosis Market size was valued at USD 9.92 billion in 2021, growing at a significant CAGR of 17.8% from 2022–2028. The market is anticipated to expand during the forecast period due to rising research expenditures. Only one firm currently offers treatments for the rare hereditary illness alpha mannosidosis. However, several businesses are developing items that will drive up demand in the market throughout the projection period. For example, the EU clinical trials database includes 39,219 clinical trials with a EudraCT protocol in 2020, 6,426 of which involve participants under 18. Therefore, the alpha mannosidosis market is expanding due to rising research expenditures. The alpha mannosidosis market is starting to notice treatment innovations such as pharmaceutical therapy. For instance, the European Medicines Agency Committee for Medicinal Products for Human Use has approved Velmanase Alfa's marketing authorization under the trade name Lamzede, according to Chiesi Group, a global healthcare firm focusing on research. To replace or supplement natural alpha-mannosidase, which aids in the breakdown of mannose-rich oligosaccharides and inhibits their build-up in various bodily tissues, Lamzede is an enzyme replacement therapy. Based on market trends, strategies for alpha mannosidosis include expanding enzyme therapy, implementing hematopoietic stem cell transplantation, and implementing cisterna magna infusion.
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Market exclusivity of orphan drugs, reimbursement for therapies, Regulatory support, incentives for orphan drug manufacturers, increase in investments in genetic therapies, growth in research and development, increase in healthcare spending, and market exclusivity of orphan drugs will all contribute to the market's expansion. The coronavirus pandemic, high orphan medication, therapy costs, and reduced healthcare spending all impacted the industry.
The alpha mannosidosis market is projected to expand at a CAGR of 17.8% during the forecast period.
Chiesi Farmaceutici S.p.A., Nuo Therapeutics, Zymenex
Asia Pacific is the fastest-growing region for alpha mannosidosis market