Coagulation Factor Deficiency Market: By Deficiency Type (Hemophilia A, Hemophilia B, Von Willebrand Disease, Factor XI Deficiency, Factor XIII Deficiency, and Others), By Product Type (Plasma-Derived Coagulation Factor Concentrates, Recombinant Coagulation Factor Concentrates, Biologics, Desmopressin, and Others), By End Users (Hospitals, Clinics, Homecare, Others) and Geography

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Coagulation Factor Deficiency Market was valued at USD 14.2 billion in 2022 and is poised to grow at a CAGR of 6.7% over 2023-2029. Coagulation factor deficiency is a rare condition that affects the blood’s ability to clot normally and can be caused by genetic mutations, acquired disease, or medications. Based on the treatment type, enzyme replacement therapy is anticipated to dominate the coagulation factor deficiency market share over the forecast period. According to the World Federation of Hemophilia, there were around 1,95,263 people worldwide who had been diagnosed with hemophilia and 80,302 people who had been diagnosed with von Willebrand disease in 2019. The increasing incidences of blood-related disorders and increasing awareness of the disease will act as the coagulation factor deficiency market growth driver. However, the high cost of treatment would be the lagging factor for the market. Unmet needs for bleeding disorders, the evolving healthcare infrastructure, and increasing disposable incomes will be opportunities for market expansion.

Coagulation Factor Deficiency Market Key Developments:
  • In Nov 2022, The US FDA approved CSL Behring’s Hemgenix (Etranacongene Dezaparvovec), an adeno-associated virus vector-based gene therapy, for the treatment of adults with hemophilia A and B.
  • In Feb 2023, Sanofi received approval of the US FDA for Efanesoctocog alfa, a high-sustained factor VIII replacement therapy, for the treatment of hemophilia A in adults.

Coagulation Factor Deficiency Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

6.7%

Largest Market

North America

Fastest Growing Market

North America
Coagulation Factor Deficiency Market Dynamics

An increase in funding by non-government and government organizations and a rise in the research and development activities by key market players are the major factors driving the market growth. For instance, in Sep 2022, the National Hemophilia Foundation announced that they had launched Pathway to Cures, a new venture philanthropy investment fund, under which the organization granted about USD 3.5 million in funding for research on blood-related disorders. Additionally, in Dec 2022, Pfizer announced positive top-line results from the phase-III Benegene-2 study for Fidanacogene Elaparvovec, an investigational gene therapy, for the treatment of adult males with moderate to severe hemophilia B. Thus, the increased awareness, research, and development for bleeding disorders will lead to market growth within the forecast period. However, high treatment costs for bleeding disorder treatment products coupled with limited reimbursement could hamper the growth of the market.

Key Features of the Reports

  • The coagulation factor deficiency market report provides granular level information about the market size, regional market share, historic market (2018-2022) and forecast (2023-2029)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Coagulation Factor Deficiency Market Segmentation

By Deficiency Type
  • Hemophilia A
  • Hemophilia B
  • Von Willebrand Disease
  • Factor XI Deficiency
  • Factor XIII Deficiency
  • Others
By Product Type
  • Plasma-derived coagulation Factor Concentrates
  • Recombinant Coagulation Factor Concentrates
  • Biologics
  • Desmopressin
  • Others
By End User
  • Hospitals
  • Clinics
  • Homecare
  • Others

Frequently Asked Questions

The Coagulation Factor Deficiency market was valued at USD 14.2 million in 2022 and is expected to grow at a 6.7% CAGR over the forecast period 2023 – 2029.

Unmet needs for bleeding disorders, the evolving healthcare infrastructure, and increasing disposable incomes are the key opportunities for the Coagulation Factor Deficiency market.

The increasing incidences of blood-related disorders and increasing awareness of the disease are the growth drivers in the Coagulation Factor Deficiency market.

Pfizer Inc, Grifols, Biogen, Octapharma, Baxter, Bayer, CSL Behring, Novo Nordisk, Greencross, Kedrion, BPL, Hualan Bio, and RAAS are a few companies operating in the Coagulation Factor Deficiency market.

1.Executive Summary
2.Global Coagulation Factor Deficiency Market Introduction 
2.1.Global Coagulation Factor Deficiency Market  - Taxonomy
2.2.Global Coagulation Factor Deficiency Market  - Definitions
2.2.1.Deficiency Type
2.2.2.Product Type
2.2.3.End Users
2.2.4.Region
3.Global Coagulation Factor Deficiency Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Coagulation Factor Deficiency Market Analysis, 2018 - 2022 and Forecast 2023 - 2029
4.1.  Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Coagulation Factor Deficiency Market  By Deficiency Type, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
5.1. Hemophilia A
5.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Hemophilia B
5.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Von Willebrand Disease
5.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Factor XI Deficiency
5.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
5.5. Factor XIII Deficiency
5.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.5.3. Market Opportunity Analysis 
5.6. Others
5.6.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.6.3. Market Opportunity Analysis 
6.Global Coagulation Factor Deficiency Market  By Product Type, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
6.1. Plasma-derived coagulation Factor Concentrates
6.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Recombinant Coagulation Factor Concentrates
6.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. Biologics
6.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
6.4. Desmopressin
6.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.4.3. Market Opportunity Analysis 
6.5. Others
6.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.5.3. Market Opportunity Analysis 
7.Global Coagulation Factor Deficiency Market  By End Users, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
7.1. Hospitals
7.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Clinics
7.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Homecare
7.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Others
7.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
8.Global Coagulation Factor Deficiency Market  By Region, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
8.1. North America
8.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Europe
8.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Asia Pacific (APAC)
8.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
8.4. Middle East and Africa (MEA)
8.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.4.3. Market Opportunity Analysis 
8.5. Latin America
8.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.5.3. Market Opportunity Analysis 
9.North America Coagulation Factor Deficiency Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
9.1. Deficiency Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Hemophilia A
9.1.2.Hemophilia B
9.1.3.Von Willebrand Disease
9.1.4.Factor XI Deficiency
9.1.5.Factor XIII Deficiency
9.1.6.Others
9.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Plasma-derived coagulation Factor Concentrates
9.2.2.Recombinant Coagulation Factor Concentrates
9.2.3.Biologics
9.2.4.Desmopressin
9.2.5.Others
9.3.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Hospitals
9.3.2.Clinics
9.3.3.Homecare
9.3.4.Others
9.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1.United States of America (USA)
9.4.2.Canada
10.Europe Coagulation Factor Deficiency Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
10.1. Deficiency Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Hemophilia A
10.1.2.Hemophilia B
10.1.3.Von Willebrand Disease
10.1.4.Factor XI Deficiency
10.1.5.Factor XIII Deficiency
10.1.6.Others
10.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Plasma-derived coagulation Factor Concentrates
10.2.2.Recombinant Coagulation Factor Concentrates
10.2.3.Biologics
10.2.4.Desmopressin
10.2.5.Others
10.3.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Hospitals
10.3.2.Clinics
10.3.3.Homecare
10.3.4.Others
10.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Germany
10.4.2.France
10.4.3.Italy
10.4.4.United Kingdom (UK)
10.4.5.Spain
10.4.6.Rest of EU
11.Asia Pacific (APAC) Coagulation Factor Deficiency Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
11.1. Deficiency Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Hemophilia A
11.1.2.Hemophilia B
11.1.3.Von Willebrand Disease
11.1.4.Factor XI Deficiency
11.1.5.Factor XIII Deficiency
11.1.6.Others
11.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Plasma-derived coagulation Factor Concentrates
11.2.2.Recombinant Coagulation Factor Concentrates
11.2.3.Biologics
11.2.4.Desmopressin
11.2.5.Others
11.3.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Hospitals
11.3.2.Clinics
11.3.3.Homecare
11.3.4.Others
11.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.China
11.4.2.India
11.4.3.Australia and New Zealand (ANZ)
11.4.4.Japan
11.4.5.Rest of APAC
12.Middle East and Africa (MEA) Coagulation Factor Deficiency Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
12.1. Deficiency Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Hemophilia A
12.1.2.Hemophilia B
12.1.3.Von Willebrand Disease
12.1.4.Factor XI Deficiency
12.1.5.Factor XIII Deficiency
12.1.6.Others
12.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Plasma-derived coagulation Factor Concentrates
12.2.2.Recombinant Coagulation Factor Concentrates
12.2.3.Biologics
12.2.4.Desmopressin
12.2.5.Others
12.3.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Hospitals
12.3.2.Clinics
12.3.3.Homecare
12.3.4.Others
12.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.GCC Countries
12.4.2.South Africa
12.4.3.Rest of MEA
13.Latin America Coagulation Factor Deficiency Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
13.1. Deficiency Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Hemophilia A
13.1.2.Hemophilia B
13.1.3.Von Willebrand Disease
13.1.4.Factor XI Deficiency
13.1.5.Factor XIII Deficiency
13.1.6.Others
13.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Plasma-derived coagulation Factor Concentrates
13.2.2.Recombinant Coagulation Factor Concentrates
13.2.3.Biologics
13.2.4.Desmopressin
13.2.5.Others
13.3.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Hospitals
13.3.2.Clinics
13.3.3.Homecare
13.3.4.Others
13.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Brazil
13.4.2.Mexico
13.4.3.Rest of LA
14. Competition Landscape
14.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
14.2.1.Pfizer Inc
14.2.2.Grifols
14.2.3.Biogen
14.2.4.Octapharma
14.2.5.Baxter
14.2.6.Bayer
14.2.7.CSL Behring
14.2.8.Novo Nordisk
14.2.9.Greencross
14.2.10.Kedrion
14.2.11.BPL
14.2.12.Hualan Bio
15. Research Methodology 
16. Appendix and Abbreviations 
  • Pfizer Inc
  • Grifols
  • Biogen
  • Octapharma
  • Baxter
  • Bayer
  • CSL Behring
  • Novo Nordisk
  • Greencross
  • Kedrion
  • BPL
  • Hualan Bio
  • RAAS

Adjacent Markets