Corneal Epithelial Defect Market: By Clinical Causes (Inflammatory Disease, Neurotrophic Keratitis (NK), Epithelial/Limbal Stem Cell Deficiency, Others), Type (Devices, Medication), End User (Hospital/Clinical Laboratories, Physician Offices, Reference Laboratories and Other End Users), Distribution Channel (Direct Tender, Retail Sales and Other), and Geography

Purchase Option

$ 4400
$ 6600
$ 8900

Corneal Epithelial Defect Market was valued at USD 7,693.5 million in 2022 and is expected to grow at 7.3% CAGR over the forecast years. Corneal Epithelial Defect (CED) is a medical condition characterized by the partial or complete loss of the outermost layer of the cornea, known as the corneal epithelium. This condition can result from various factors such as trauma, infections, dry eye syndrome, or corneal dystrophy. The market for CED treatment encompasses a range of therapeutic options, including medications, bandage contact lenses, amniotic membrane transplantation, and innovative regenerative therapies.

According to data from the World Health Organization (WHO), corneal diseases and conditions collectively account for a significant proportion of global blindness and visual impairment, and in 2021, an estimated 4.2 million individuals worldwide were blind due to corneal diseases, with an additional 23.9 million people experiencing moderate to severe visual impairment. The prevalence of CED may vary among different regions and populations. For instance, the National Eye Institute (NEI) in the United States reported that corneal abrasions, which can lead to epithelial defects, accounted for approximately 10% of all eye injuries in the country in 2020. Moreover, CED often poses challenges in the management of other ocular conditions, such as recurrent corneal erosions, affecting about 6% of the population.

In recent years, there has been a growing focus on advanced treatment options for CED. Research and development efforts have resulted in innovative therapies, such as bioengineered corneal epithelial substitutes and gene therapies aimed at promoting tissue healing and regeneration. These emerging therapies show promise in reducing healing time, minimizing scarring, and improving overall patient outcomes. Given the significant burden of corneal diseases and the potential impact on vision, governments and healthcare organizations worldwide are investing in research, awareness campaigns, and access to quality eye care services. The increasing prevalence of risk factors like dry eye syndrome and ocular trauma underlines the importance of continuous efforts to address Corneal Epithelial Defects effectively and sustainably.

Corneal Epithelial Defect Market Key Developments:

In October 2017, Bio-Tisssue entered a strategic agreement with Optima Pharmazeutische GmbH, a pharma company that offers otorhinolaryngology, ophthalmology, and pneumology products. This agreement helps the company to distribute its natural Ocular cleanser in Germany.

Corneal Epithelial Defect Market Summary

Study Period


Base Year




Largest Market

North America

Fastest Growing Market

North America
Corneal Epithelial Defect Market Dynamics

The market for Corneal Epithelial Defect (CED) is poised for substantial growth, primarily driven by several factors. Firstly, advancements in ophthalmic diagnostic technologies and an increasing focus on early disease detection are propelling demand for CED treatments. Moreover, the rising prevalence of corneal disorders and ocular injuries, coupled with an aging population, is creating a larger patient pool seeking effective remedies for CED. Additionally, innovations in regenerative medicine and tissue engineering are opening new avenues for novel and more efficient therapeutic solutions. Furthermore, the growing adoption of minimally invasive surgical procedures and the availability of customized treatment options are enhancing patient outcomes and driving market expansion. The potential opportunities lie in the development of more cost-effective and scalable treatment methods, as well as in expanding market penetration in untapped regions globally. As the awareness about CED and its management rises, the market is expected to witness sustained growth in the foreseeable future.

Key Features of the Reports

  • The corneal epithelial defect market report provides granular level information about the market size, regional market share, historic market (2018-2022), and forecast (2023-2029)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Corneal Epithelial Defect Market Segmentation

By Type
  • Devices
  • Medication
By Distribution Channel
  • Direct Tender
  • Retail Sales
  • Other
By End User
  • Hospital/Clinical Laboratories
  • Physician Offices
  • Reference Laboratories
  • Other

Frequently Asked Questions

The corneal epithelial defect market was valued at USD 7,693.5 million in 2022 and is expected to grow at 7.3% CAGR over the forecast period 2023 – 2029.

Key opportunities for the Corneal Epithelial Defect market include advanced regenerative therapies, innovative bioengineered corneal substitutes, and increased investment in research and development for faster healing and improved patient outcomes.

Key trends in the Corneal Epithelial Defect market include a shift towards personalized treatment approaches, growing adoption of gene therapies, advancements in regenerative medicine, and an increasing focus on patient-centric care.

Novartis AG (Switzerland), Abbvie, Inc. (U.S.), Johnson & Johnson Services, Inc. (U.S.), Laboratoires Théa (France), Almirall, S.A (Spain), Ocular Science (U.S.), Kala Pharmaceuticals (U.S.), Bausch Health Companies Inc (Canada), Integra LifeSciences (U.S.), and BioTissue (Florida) are a few prominent companies operating in the field of Corneal Epithelial Defect market.

  • NovartisAG(Switzerland)
  • Abbvie,Inc(U.S.)
  • Johnson&JohnsonServices,Inc.(U.S.)
  • LaboratoiresThéa.(France)
  • Almirall,S.A(Spain)
  • OcularScience(U.S.)
  • KalaPharmaceuticals(U.S.)
  • BauschHealthCompaniesInc(Canada)
  • IntegraLifeSciences(U.S.)
  • BioTissue(Florida)

Adjacent Markets