Cystic Fibrosis Pipeline Drugs Assessment: Clinical Trials Analysis, Player Profiles, Collaborations, Key Targets, Geographic Focus, and Data Publications, 2018  

Cystic fibrosis is a inherited disease, enables damage lungs, gastro-intestinal tract and other parts of the body. Cystic fibrosis occur due to defective gene and affects the secreting cells of the body and causes thickening of the body fluids such as muscus, sweat and digestive juices. These body fluids plung up the ducts, tubes and passages, especially in lungs and pancreas. Cystic Fibriosis signs and syptoms develops along with the severity of the disease. Patients may have excess of salt content in sweat than normal and reoccurs pneumonia. Diagnostictests include sweat tests and genetic tests. There is no cure for the disease. Medications are used to treat the disease and reduce the symptoms. Medications may include, mucus thinning agents, antibiotics, anti inflamatory, inhalation brancodialators and others.  

 Key deve;lopments: 

• In October 2016, Celtaxsys announced publication of results demonstrating safety, tolerability and pharmacokinetic & dynamic profile of novel anti-inflammatory medicine, Acebilustat, in phase I trials including CF patients.