- Membrane Adsorbents
- Chromatography Columns and Resins
- Filters
- Others
Downstream Processing Market size was estimated at USD 23.9 billion in 2022 and is poised to grow at a significant CAGR of 15.6% from 2023- 2029. Downstream processing is the process of recovery and purification of the biosynthetic products. Biosynthetic products particularly pharmaceuticals, from natural sources such as plant or animal tissue or fermentation broth. Downstream processing market may also include recycling of salvageable components and proper treatment of waste. Furthermore, downstream processing is important step in manufacturing of hormones, antibiotics, antibodies, and vaccines. Stages include removal of insoluble, product isolation, product purification, product polishing and few recovery methods may be considered. The market is expected to grow at significant rates owing to the rise in demand for biopharmaceutical products. The market is consolidated due to presence of the many companies competing with product innovations and advancements. Companies are focusing on the R&D and new product launches to increase their product portfolio.
Downstream Processing Market Key Developments :
- In November 2012, Asahi Kasie Medical Co. Ltd. Has launched 5 L QyuSpeed D membrane adsorbers, designed specifically for removal of impurities in bioprocessing. In the product segment, chromatographic columns and resins are expected to have significant growth rate owing to the technological advancements in chromatography techniques and new product launches.
Downstream Processing Market Summary
Study Period
2024-2030
Base Year
2023
CAGR
15.6%
Largest Market
North America
Fastest Growing Market
Asia-Pacific
Downstream Processing Market Dynamics
The market is mainly driven by the rise in R&D investment by the companies and government in the biopharmaceutical industry to produce more effective biopharmaceuticals. In addition, propelling demand for biopharmaceuticals due to the rising prevalence of communicable diseases and chronic diseases such as cancer boosting the market growth over the forecast period. Furthermore, technological developments in purification technology and need for highly pure biopharmaceuticals such as vaccines bolstering the global downstream processing market. However, lack of skilled professionals, high cost of devices and regulatory procedures are expected to hamper the market during the forecast period.
North-America Got Significant Share
Downstream Processing Market Regional Analysis
North America downstream processing market is expected to have major share in market owing to factors such as rise in R&D investment by the companies and government to develop new biopharmaceuticals for communicable diseases and cancer. Europe is expected to expand at unprecedented growth rate owing to presence of key biopharmaceutical companies and significant growth in a number of market players. Asia Pacific is projected to be fastest growing market in global downstream processing market. The growth is attributed to surge in contract manufacturing organizations, increase in company and governments in product developments.
Latin America
Europe
Asia Pacific
Middle East
North America
Key Features of the Reports
- The report provides granular level information about the market size, regional market share, historic market (2018 to 2022) and forecast (2023 to 2029)
- The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
- The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
- The report tracks recent innovations, key developments and startup’s details that are actively working in the market
- The report provides plethora of information about market entry strategies, regulatory framework and reimbursement scenario
- The report analyses the impact of socio-political environment through PESTLE Analysis and competition through Porter’s Five Force Analysis in addition to recent technology advancements and innovations in the market
Downstream Processing Market Segmentation
By Product Type
By Technique
- Purification Techniques
- Gel Chromatography
- Ion Exchange Chromatography
- Affinity Chromatography
- Hydrophobic Interaction Chromatography
- Solid-Liquid Separation
- Filtration
- Centrifugation
- Concentration/Clarification
By Application
- Vaccine Production
- Monoclonal Antibodies Production
- Insulin Production
- Erythropoietin Production
- Immunoglobulin Production
- Others
By End User
- Biopharmaceutical Manufacturers
- Contract Manufacturing Organizations
- Others
Frequently Asked Questions
2022 is the base year and 2029 is the forecast year.
The report covers the five regions and 15+ countries market data: North America (United States, Canada), Europe (Germany, France, Italy, Spain, and United Kingdom (UK), Asia Pacific (China, India, Japan, Australia & New Zealand), Latin America (Brazil, Mexico, Argentina) and Middle East and Africa (Saudi Arabia, United Arab Emirates, South Africa).
In our report, we provide 12-15 market players’ information into the report. However, based on the client’s request we will provide additional country and regional market players information as well.
Downstream Processing Market size was estimated at USD 23.9 billion in 2022.
The key trend in the downstream processing market is the growing adoption of single-use technologies to improve flexibility and reduce operational costs in biopharmaceutical manufacturing processes.
| 1.Executive Summary |
| 2.Global Downstream Processing Market Introduction |
| 2.1.Global Downstream Processing Market - Taxonomy |
| 2.2.Global Downstream Processing Market - Definitions |
| 2.2.1.Product Type |
| 2.2.2.Technique |
| 2.2.3.Application |
| 2.2.4.End User |
| 2.2.5.Region |
| 3.Global Downstream Processing Market Dynamics |
| 3.1. Drivers |
| 3.2. Restraints |
| 3.3. Opportunities/Unmet Needs of the Market |
| 3.4. Trends |
| 3.5. Product Landscape |
| 3.6. New Product Launches |
| 3.7. Impact of COVID 19 on Market |
| 4.Global Downstream Processing Market Analysis, 2018-2022 and Forecast 2023-2029 |
| 4.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) |
| 4.3. Market Opportunity Analysis |
| 5.Global Downstream Processing Market By Product Type, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 5.1. Membrane Adsorbents |
| 5.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.1.3. Market Opportunity Analysis |
| 5.2. Chromatography Columns and Resins |
| 5.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.2.3. Market Opportunity Analysis |
| 5.3. Filters |
| 5.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.3.3. Market Opportunity Analysis |
| 5.4. Others |
| 5.4.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.4.3. Market Opportunity Analysis |
| 6.Global Downstream Processing Market By Technique, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 6.1. Purification Techniques |
| 6.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 6.1.3. Market Opportunity Analysis |
| 6.2. Concentration/Clarification |
| 6.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 6.2.3. Market Opportunity Analysis |
| 7.Global Downstream Processing Market By Application, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 7.1. Vaccine Production |
| 7.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.1.3. Market Opportunity Analysis |
| 7.2. Monoclonal Antibodies Production |
| 7.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.2.3. Market Opportunity Analysis |
| 7.3. Insulin Production |
| 7.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.3.3. Market Opportunity Analysis |
| 7.4. Erythropoietin Production |
| 7.4.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.4.3. Market Opportunity Analysis |
| 7.5. Immunoglobulin Production |
| 7.5.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 7.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.5.3. Market Opportunity Analysis |
| 7.6. Others |
| 7.6.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 7.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.6.3. Market Opportunity Analysis |
| 8.Global Downstream Processing Market By End User, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 8.1. Biopharmaceutical Manufacturers |
| 8.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.1.3. Market Opportunity Analysis |
| 8.2. Contract Manufacturing Organizations |
| 8.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.2.3. Market Opportunity Analysis |
| 8.3. Others |
| 8.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.3.3. Market Opportunity Analysis |
| 9.Global Downstream Processing Market By Region, 2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 9.1. North America |
| 9.1.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 9.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 9.1.3. Market Opportunity Analysis |
| 9.2. Europe |
| 9.2.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 9.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 9.2.3. Market Opportunity Analysis |
| 9.3. Asia Pacific (APAC) |
| 9.3.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 9.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 9.3.3. Market Opportunity Analysis |
| 9.4. Middle East and Africa (MEA) |
| 9.4.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 9.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 9.4.3. Market Opportunity Analysis |
| 9.5. Latin America |
| 9.5.1. Market Analysis, 2018-2022 and Forecast, 2023-2029, (Sales Value USD Million) |
| 9.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 9.5.3. Market Opportunity Analysis |
| 10.North America Downstream Processing Market ,2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 10.1. Product Type Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.1.1.Membrane Adsorbents |
| 10.1.2.Chromatography Columns and Resins |
| 10.1.3.Filters |
| 10.1.4.Others |
| 10.2. Technique Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.2.1.Purification Techniques |
| 10.2.2.Concentration/Clarification |
| 10.3. Application Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.3.1.Vaccine Production |
| 10.3.2.Monoclonal Antibodies Production |
| 10.3.3.Insulin Production |
| 10.3.4.Erythropoietin Production |
| 10.3.5.Immunoglobulin Production |
| 10.3.6.Others |
| 10.4. End User Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.4.1.Biopharmaceutical Manufacturers |
| 10.4.2.Contract Manufacturing Organizations |
| 10.4.3.Others |
| 10.5. Country Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.5.1.United States of America (USA) |
| 10.5.2.Canada |
| 11.Europe Downstream Processing Market ,2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 11.1. Product Type Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.1.1.Membrane Adsorbents |
| 11.1.2.Chromatography Columns and Resins |
| 11.1.3.Filters |
| 11.1.4.Others |
| 11.2. Technique Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.2.1.Purification Techniques |
| 11.2.2.Concentration/Clarification |
| 11.3. Application Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.3.1.Vaccine Production |
| 11.3.2.Monoclonal Antibodies Production |
| 11.3.3.Insulin Production |
| 11.3.4.Erythropoietin Production |
| 11.3.5.Immunoglobulin Production |
| 11.3.6.Others |
| 11.4. End User Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.4.1.Biopharmaceutical Manufacturers |
| 11.4.2.Contract Manufacturing Organizations |
| 11.4.3.Others |
| 11.5. Country Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.5.1.Germany |
| 11.5.2.France |
| 11.5.3.Italy |
| 11.5.4.United Kingdom (UK) |
| 11.5.5.Spain |
| 11.5.6.Rest of EU |
| 11.5.7. |
| 12.Asia Pacific (APAC) Downstream Processing Market ,2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 12.1. Product Type Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.1.1.Membrane Adsorbents |
| 12.1.2.Chromatography Columns and Resins |
| 12.1.3.Filters |
| 12.1.4.Others |
| 12.2. Technique Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.2.1.Purification Techniques |
| 12.2.2.Concentration/Clarification |
| 12.3. Application Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.3.1.Vaccine Production |
| 12.3.2.Monoclonal Antibodies Production |
| 12.3.3.Insulin Production |
| 12.3.4.Erythropoietin Production |
| 12.3.5.Immunoglobulin Production |
| 12.3.6.Others |
| 12.4. End User Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.4.1.Biopharmaceutical Manufacturers |
| 12.4.2.Contract Manufacturing Organizations |
| 12.4.3.Others |
| 12.5. Country Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.5.1.China |
| 12.5.2.India |
| 12.5.3.Australia and New Zealand (ANZ) |
| 12.5.4.Japan |
| 12.5.5.Rest of APAC |
| 13.Middle East and Africa (MEA) Downstream Processing Market ,2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 13.1. Product Type Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.1.1.Membrane Adsorbents |
| 13.1.2.Chromatography Columns and Resins |
| 13.1.3.Filters |
| 13.1.4.Others |
| 13.2. Technique Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.2.1.Purification Techniques |
| 13.2.2.Concentration/Clarification |
| 13.3. Application Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.3.1.Vaccine Production |
| 13.3.2.Monoclonal Antibodies Production |
| 13.3.3.Insulin Production |
| 13.3.4.Erythropoietin Production |
| 13.3.5.Immunoglobulin Production |
| 13.3.6.Others |
| 13.4. End User Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.4.1.Biopharmaceutical Manufacturers |
| 13.4.2.Contract Manufacturing Organizations |
| 13.4.3.Others |
| 13.5. Country Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.5.1.GCC Countries |
| 13.5.2.South Africa |
| 13.5.3.Rest of MEA |
| 14.Latin America Downstream Processing Market ,2018-2022 and Forecast 2023-2029 (Sales Value USD Million) |
| 14.1. Product Type Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 14.1.1.Membrane Adsorbents |
| 14.1.2.Chromatography Columns and Resins |
| 14.1.3.Filters |
| 14.1.4.Others |
| 14.2. Technique Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 14.2.1.Purification Techniques |
| 14.2.2.Concentration/Clarification |
| 14.3. Application Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 14.3.1.Vaccine Production |
| 14.3.2.Monoclonal Antibodies Production |
| 14.3.3.Insulin Production |
| 14.3.4.Erythropoietin Production |
| 14.3.5.Immunoglobulin Production |
| 14.3.6.Others |
| 14.4. End User Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 14.4.1.Biopharmaceutical Manufacturers |
| 14.4.2.Contract Manufacturing Organizations |
| 14.4.3.Others |
| 14.5. Country Analysis 2018-2022 and Forecast 2023-2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 14.5.1.Brazil |
| 14.5.2.Mexico |
| 14.5.3.Rest of LA |
| 15. Competition Landscape |
| 15.1. Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) |
| 15.2.1.Boehringer Ingelheim GmbH (Germany) |
| 15.2.2.3M Company (U.S.) |
| 15.2.3.Eppendorf AG (Germany) |
| 15.2.4.Danaher Corporation (U.S.) |
| 15.2.5.General Electric (U.S.) |
| 15.2.6.Finesse Solutions, Inc. (Thermo Fisher Scientific) (U.S.) |
| 15.2.7.Merck KGaA (Germany) |
| 15.2.8.Lonza Group AG (Switzerland) |
| 16. Research Methodology |
| 17. Appendix and Abbreviations |
- Boehringer Ingelheim GmbH (Germany)
- 3M Company (U.S.)
- Eppendorf AG (Germany)
- Danaher Corporation (U.S.)
- General Electric (U.S.)
- Finesse Solutions, Inc. (Thermo Fisher Scientific) (U.S.)
- Merck KGaA (Germany)
- Lonza Group AG (Switzerland)