Protein Expression Services Market: By System (Prokaryotic Expression Systems, Mammalian Expression Systems, Yeast Cell Expression Systems, Insect Cell Expression Systems, Cell-free Expression Systems  and Others ), By Product (Reagents, Competent Cells, Instruments, and Services), By Application (Therapeutic, Research, and Industrial), By End-use Industry (Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, CROs, and Others), and Geography

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Protein Expression Services Market size was valued at USD 532.8 million in 2022 and is poised to grow at a significant CAGR of 5.6% from 2023-2029. Protein expression is the process of directing the synthesis of large numbers of desired proteins in an organism, usually by controlling gene expression to generate a significant amount of a recombinant gene. The increasing frequency of chronic diseases, expansion in the elderly population, and the rising need for protein biologics drive the worldwide protein expression market forward. The necessity for large-scale manufacturing of therapeutic proteins to treat infectious and chronic diseases has grown as the prevalence of these diseases has increased. Rapid advancements in recombinant DNA technology have paved the way for the development of recombinant proteins that can be employed as medicines, vaccines, and diagnostic reagents. Strong demand for biopharmaceuticals has prompted the development of new protein expression hosts and bioprocessing technologies, which have enhanced protein yield while lowering prices, and this is projected to continue to fuel market expansion in the future.

In the protein expression services market, developments in technology such as mass spectrometry, molecular genetics, and manufacturing techniques are all major drivers. Furthermore, significant advancements in medical technology, improved disease identification, and the expansion of healthcare in new economies should all benefit the industry. Based on the product, due to the increased use of reagents in research studies and biologics production, the reagents segment revenue is predicted to grow significantly during the projection period. This segment's revenue growth is predicted to be fueled by increased demand for reagents and rising spending on reagents and kits for industrial, therapeutic, and research applications. Protein expression products for research and manufacturing are becoming more popular due to the availability of improved and new technologies to meet the needs of pharmaceutical and biologics product makers. In addition, various pharmaceutical and biotechnology companies are forming alliances and collaborations in order to gain market leadership.

Protein Expression Services Market Key Developments:
  • In Jan 2022,  Thermo Fisher Scientific Inc., the world leader in serving science, and PeproTech, Inc., a leading developer and manufacturer of recombinant proteins, has completed its acquisition of PeproTech on December 30, 2021 for a total cash purchase price of approximately $1.85 billion.
  • In October 2021, Promega Launched Sanger Sequencing Chemistry Compatible With All Capillary Electrophoresis Platforms. ProDyeâ„¢ Terminator Sequencing System brings Sanger sequencing to any size laboratory.

Global Protein Expression Services Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

5.6%

Largest Market

Asia Pacific

Fastest Growing Market

North America
Protein Expression Services Market Dynamics

A prominent driver predicted to fuel revenue growth in the market over the forecast period is rising demand for protein therapies, owing to various advantages over small-molecule medicines. Over the projected timeframe, the market is anticipated to increase in revenue due to increasing research into recombinant protein expression. However, the high cost of protein expression reagents and instruments, along with increasing consolidation and high barriers for new entrants, will hinder the market growth. High monetary inputs associated with the production of protein products also restrict the growth of the market.

Key Features of the Reports

  • The report provides granular level information about the market size, regional market share, historic market (2019-2023), and forecast (2024-2030)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Global Protein Expression Services Market Segmentation

By System Type
  • Prokaryotic Expression Systems
    • Escherichia coli Systems
    • Others
  • Mammalian Expression Systems
  • Yeast Cell Expression Systems
    • Kluyveromyces Lactis Systems
    • Saccharomyces Systems
    • Pichia Systems
    • Other Systems
  • Insect Cell Expression Systems
    • Baculovirus Expression Systems
    • Other Systems
  • Cell-free Expression Systems
  • Others
By Product Type
  • Academic & Research Institutes
  • Pharmaceutical & Biotechnology Companies
  • CROs
  • Others
By End-User
  • Pharmaceutical and Biological Manufacturing
  • Medical Devices Manufacturing
  • Other Applications

Frequently Asked Questions

The protein expression services market size was valued at USD 532.8 million in 2022

Agilent Technologies, Inc., Thermo Fisher Scientific Inc., Bio-Rad Laboratories, Inc., Merck KGaA, Promega Corporation, New England Biolabs

North America is the fastest-growing region for protein expression services market

1.Executive Summary
2.Global Protein Expression Services Market Introduction 
2.1.Global Protein Expression Services Market  - Taxonomy
2.2.Global Protein Expression Services Market  - Definitions
2.2.1.  By System Type
2.2.2. By Product Type
2.2.3. By End User
2.2.4. By Region
3.Global Protein Expression Services Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Protein Expression Services Market Analysis, 2018 - 2022 and Forecast 2023 - 2029
4.1.  Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Protein Expression Services Market  By  System Type, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
5.1. Prokaryotic Expression Systems 
5.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Mammalian Expression Systems
5.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Yeast Cell Expression Systems 
5.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Insect Cell Expression Systems 
5.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
5.5. Cell-free Expression Systems
5.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.5.3. Market Opportunity Analysis 
5.6. Others
5.6.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.6.3. Market Opportunity Analysis 
6.Global Protein Expression Services Market  By Product Type, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
6.1. Academic & Research Institutes
6.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Pharmaceutical & Biotechnology Companies
6.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. CROs
6.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
6.4. Others
6.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.4.3. Market Opportunity Analysis 
7.Global Protein Expression Services Market  By End User, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
7.1. Pharmaceutical and Biological Manufacturing
7.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Medical Devices Manufacturing
7.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Other Applications
7.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
8.Global Protein Expression Services Market  By Region, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
8.1. North America
8.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Europe
8.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Asia Pacific (APAC)
8.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
8.4. Middle East and Africa (MEA)
8.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.4.3. Market Opportunity Analysis 
8.5. Latin America
8.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.5.3. Market Opportunity Analysis 
9.North America Protein Expression Services Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
9.1.  System Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Prokaryotic Expression Systems 
9.1.2.Mammalian Expression Systems
9.1.3.Yeast Cell Expression Systems 
9.1.4.Insect Cell Expression Systems 
9.1.5.Cell-free Expression Systems
9.1.6.Others
9.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Academic & Research Institutes
9.2.2.Pharmaceutical & Biotechnology Companies
9.2.3.CROs
9.2.4.Others
9.3.  End User Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Pharmaceutical and Biological Manufacturing
9.3.2.Medical Devices Manufacturing
9.3.3.Other Applications
9.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1.United States of America (USA)
9.4.2.Canada
10.Europe Protein Expression Services Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
10.1.  System Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Prokaryotic Expression Systems 
10.1.2.Mammalian Expression Systems
10.1.3.Yeast Cell Expression Systems 
10.1.4.Insect Cell Expression Systems 
10.1.5.Cell-free Expression Systems
10.1.6.Others
10.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Academic & Research Institutes
10.2.2.Pharmaceutical & Biotechnology Companies
10.2.3.CROs
10.2.4.Others
10.3.  End User Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Pharmaceutical and Biological Manufacturing
10.3.2.Medical Devices Manufacturing
10.3.3.Other Applications
10.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Germany
10.4.2.France
10.4.3.Italy
10.4.4.United Kingdom (UK)
10.4.5.Spain
11.Asia Pacific (APAC) Protein Expression Services Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
11.1.  System Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Prokaryotic Expression Systems 
11.1.2.Mammalian Expression Systems
11.1.3.Yeast Cell Expression Systems 
11.1.4.Insect Cell Expression Systems 
11.1.5.Cell-free Expression Systems
11.1.6.Others
11.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Academic & Research Institutes
11.2.2.Pharmaceutical & Biotechnology Companies
11.2.3.CROs
11.2.4.Others
11.3.  End User Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Pharmaceutical and Biological Manufacturing
11.3.2.Medical Devices Manufacturing
11.3.3.Other Applications
11.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.China
11.4.2.India
11.4.3.Australia and New Zealand (ANZ)
11.4.4.Japan
11.4.5.Rest of APAC
12.Middle East and Africa (MEA) Protein Expression Services Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
12.1.  System Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Prokaryotic Expression Systems 
12.1.2.Mammalian Expression Systems
12.1.3.Yeast Cell Expression Systems 
12.1.4.Insect Cell Expression Systems 
12.1.5.Cell-free Expression Systems
12.1.6.Others
12.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Academic & Research Institutes
12.2.2.Pharmaceutical & Biotechnology Companies
12.2.3.CROs
12.2.4.Others
12.3.  End User Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Pharmaceutical and Biological Manufacturing
12.3.2.Medical Devices Manufacturing
12.3.3.Other Applications
12.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.GCC Countries
12.4.2.South Africa
12.4.3.Rest of MEA
13.Latin America Protein Expression Services Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
13.1.  System Type Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Prokaryotic Expression Systems 
13.1.2.Mammalian Expression Systems
13.1.3.Yeast Cell Expression Systems 
13.1.4.Insect Cell Expression Systems 
13.1.5.Cell-free Expression Systems
13.1.6.Others
13.2.  Product Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Academic & Research Institutes
13.2.2.Pharmaceutical & Biotechnology Companies
13.2.3.CROs
13.2.4.Others
13.3.  End User Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Pharmaceutical and Biological Manufacturing
13.3.2.Medical Devices Manufacturing
13.3.3.Other Applications
13.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Brazil
13.4.2.Mexico
13.4.3.Rest of LA
14. Competition Landscape
14.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
14.2.1.Agilent Technologies, Inc.
14.2.2.Thermo Fisher Scientific Inc.
14.2.3.Bio-Rad Laboratories, Inc.
14.2.4.Merck KGaA
14.2.5.Promega Corporation
14.2.6.New England Biolabs
14.2.7.Qiagen
14.2.8.Takara Bio, Inc.
14.2.9.Genscript Biotech Corporation
14.2.10.Oxford Expression Technologies Ltd.
14.2.11.Synthetic Genomics Inc.
15. Research Methodology 
16. Appendix and Abbreviations 
  • Agilent Technologies, Inc.
  • Thermo Fisher Scientific Inc.
  • Bio-Rad Laboratories, Inc.
  • Merck KGaA
  • Promega Corporation
  • New England Biolabs
  • Qiagen
  • Takara Bio, Inc.
  • Genscript Biotech Corporation
  • Oxford Expression Technologies Ltd.
  • Synthetic Genomics Inc.

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