Paroxysmal Nocturnal Hemoglobinuria Treatment Market: By Treatment Type (Stem Cell Transplant and Blood Transfusion), By Drug Type (Anti C5 Monoclonal Antibodies, Danicopan, Iron supplements, and Others), By Distribution Channel (Retail, Hospital Pharmacies, Online Pharmacy), and Geography

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Paroxysmal Nocturnal Hemoglobinuria Treatment Market was valued at USD 6.4 billion in 2022 and is projected to reach USD 12.3 Billion by 2029, growing at a 6.2% CAGR from 2023 to 2029. Paroxysmal nocturnal hemoglobinuria (PNH) is a disorder that leads to the premature death and impaired production of blood cells, it presents clinically with a variety of symptoms, the most prevalent of which are hemolytic anemia, hemoglobinuria, and somatic symptoms including fatigue and shortness of breath, increase in the prevalence of blood disorder globally consequences rise in PNH treatment market growth, According to National Organization of Rare Diseases, The prevalence is estimated to be between 0.5-1.5 per million people in the general population, affects males and females in equal numbers, although some studies show a slightly more female affected.

The industry is influenced by continuous technological development in healthcare infrastructure along with research and development to improve specific therapies which leads to the major factor that drives the market growth. With the rising prevalence of hemoglobinuria globally the key players focusing on research and development activities and undergoing clinical trials for the treatment, in addition, the numerous approaches for the development of anti-C5 monoclonal antibodies influence the revenue growth leads to create lucrative opportunities in the Paroxysmal Nocturnal Hemoglobinuria Treatment market. To treat patients with repeated hemolysis and anemia, blood transfusion, and iron supplements were administered to cause adverse reactions, also the unavailability of specialty professionals limits the market growth, high cost of treatment hampers the emerging economics countries’ market resist the growth of Paroxysmal Nocturnal Hemoglobinuria Treatment market. 

Paroxysmal Nocturnal Hemoglobinuria Treatment Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

6.2%

Largest Market

North America

Fastest Growing Market

Asia Pacific
Paroxysmal Nocturnal Hemoglobinuria Treatment Market Dynamics

The increasing prevalence of blood disorders across the world is the major market driver in the Paroxysmal Nocturnal Hemoglobinuria Treatment market during the forecast period. Increasing incidences of hematological disorders across the globe such as anemia, bleeding disorders such as hemophilia, blood clots, and blood cancers such as leukemia, lymphoma, and myeloma seen common in the present era, demand efficient treatment and influence the market growth. The technological advancement and undergoing clinical trials drugs are offers specific therapies contributing to market development along with government initiatives for better treatment facilities drive the market growth at a significant rate.

Key Features of the Reports

  • The paroxysmal nocturnal hemoglobinuria treatment market report provides granular level information about the market size, regional market share, historic market (2018-2022), and forecast (2023-2029)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Paroxysmal Nocturnal Hemoglobinuria Treatment Market Segmentation

By Treatment
  • Stem Cell Transplant
  • Blood Transfusion
By Drug Type
  • Anti C5 monoclonal antibodies
  • Danicopan
  • Iron supplements
  • others
By Distribution Channel
  • Retail Pharmacy
  • Hospital Pharmacy
  • Online Pharmacy
By Geography
  • North America
  • Europe
  • The Asia Pacific
  • Latin America
  • MEA

Frequently Asked Questions

The paroxysmal nocturnal hemoglobinuria treatment market size was valued at USD 6.4 Billion in 2022 and is projected to reach USD 12.3 Billion by 2029,

The paroxysmal nocturnal hemoglobinuria treatment market is poised to grow at a significant CAGR of 6.2% from 2023 to 2029.

The leading players in the Paroxysmal Nocturnal Hemoglobinuria Treatment market are Novartis AG, Apellis Pharmaceuticals, AbbVie, Allergan, Novartis AG, Johnson & Johnson, Bayer AG, Takeda Pharmaceuticals, Bristol-Myers Squibb Company, Mylan N.V., Amgen Inc., Alexion Pharmaceuticals, Hoffmann-La Roche, Alexion Pharmaceuticals, Amgen Inc., GE Healthcare, Ra Pharmaceuticals, Regeneron Pharmaceuticals, Inc., and Thermo Fisher Scientific Inc.

Historic years considered for the market study are 2018 through 2022, 2022 is considered as the base year for market estimation, and Seven years forecast is presented from 2023 – 2029.

1.Executive Summary
2.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market Introduction 
2.1.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market  - Taxonomy
2.2.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market  - Definitions
2.2.1.Treatment
2.2.2.Drug Type
2.2.3.Distribution Channel
2.2.4.Region
3.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market Analysis, 2018 - 2022 and Forecast 2023 - 2029
4.1.  Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market  By Treatment, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
5.1. Stem Cell Transplant
5.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Blood Transfusion
5.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
6.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market  By Drug Type, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
6.1. Anti C5 monoclonal antibodies
6.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Danicopan
6.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. Iron supplements
6.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
6.4. others
6.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.4.3. Market Opportunity Analysis 
7.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market  By Distribution Channel, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
7.1. Retail Pharmacy
7.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Hospital Pharmacy
7.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Online Pharmacy
7.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
8.Global Paroxysmal Nocturnal Hemoglobinuria Treatment Market  By Region, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
8.1. North America
8.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Europe
8.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Asia Pacific (APAC)
8.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
8.4. Middle East and Africa (MEA)
8.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.4.3. Market Opportunity Analysis 
8.5. Latin America
8.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.5.3. Market Opportunity Analysis 
9.North America Paroxysmal Nocturnal Hemoglobinuria Treatment Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
9.1. Treatment Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Stem Cell Transplant
9.1.2.Blood Transfusion
9.2.  Drug Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Anti C5 monoclonal antibodies
9.2.2.Danicopan
9.2.3.Iron supplements
9.2.4.others
9.3.  Distribution Channel Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Retail Pharmacy
9.3.2.Hospital Pharmacy
9.3.3.Online Pharmacy
9.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1.United States of America (USA)
9.4.2.Canada
10.Europe Paroxysmal Nocturnal Hemoglobinuria Treatment Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
10.1. Treatment Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Stem Cell Transplant
10.1.2.Blood Transfusion
10.2.  Drug Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Anti C5 monoclonal antibodies
10.2.2.Danicopan
10.2.3.Iron supplements
10.2.4.others
10.3.  Distribution Channel Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Retail Pharmacy
10.3.2.Hospital Pharmacy
10.3.3.Online Pharmacy
10.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Germany
10.4.2.France
10.4.3.Italy
10.4.4.United Kingdom (UK)
10.4.5.Spain
10.4.6.Rest of EU
10.4.7.
11.Asia Pacific (APAC) Paroxysmal Nocturnal Hemoglobinuria Treatment Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
11.1. Treatment Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Stem Cell Transplant
11.1.2.Blood Transfusion
11.2.  Drug Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Anti C5 monoclonal antibodies
11.2.2.Danicopan
11.2.3.Iron supplements
11.2.4.others
11.3.  Distribution Channel Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Retail Pharmacy
11.3.2.Hospital Pharmacy
11.3.3.Online Pharmacy
11.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.China
11.4.2.India
11.4.3.Australia and New Zealand (ANZ)
11.4.4.Japan
11.4.5.Rest of APAC
12.Middle East and Africa (MEA) Paroxysmal Nocturnal Hemoglobinuria Treatment Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
12.1. Treatment Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Stem Cell Transplant
12.1.2.Blood Transfusion
12.2.  Drug Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Anti C5 monoclonal antibodies
12.2.2.Danicopan
12.2.3.Iron supplements
12.2.4.others
12.3.  Distribution Channel Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Retail Pharmacy
12.3.2.Hospital Pharmacy
12.3.3.Online Pharmacy
12.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.GCC Countries
12.4.2.South Africa
12.4.3.Rest of MEA
13.Latin America Paroxysmal Nocturnal Hemoglobinuria Treatment Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
13.1. Treatment Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Stem Cell Transplant
13.1.2.Blood Transfusion
13.2.  Drug Type Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Anti C5 monoclonal antibodies
13.2.2.Danicopan
13.2.3.Iron supplements
13.2.4.others
13.3.  Distribution Channel Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Retail Pharmacy
13.3.2.Hospital Pharmacy
13.3.3.Online Pharmacy
13.4.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Brazil
13.4.2.Mexico
13.4.3.Rest of LA
14. Competition Landscape
14.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
14.2.1.Novartis AG
14.2.2.Apellis Pharmaceuticals
14.2.3.AbbVie
14.2.4.Allergan
14.2.5.Novartis AG
14.2.6.Johnson & Johnson
14.2.7.Bayer AG
14.2.8.Takeda pharmaceuticals
14.2.9.Bristol-Myers Squibb Company
14.2.10.Mylan N.V.
14.2.11.Amgen Inc.
14.2.12.Alexion Pharmaceuticals
15. Research Methodology 
16. Appendix and Abbreviations 
  • Novartis AG
  • Apellis Pharmaceuticals
  • AbbVie
  • Allergan
  • Novartis AG
  • Johnson & Johnson
  • Bayer AG
  • Takeda pharmaceuticals
  • Bristol-Myers Squibb Company
  • Mylan N.V.
  • Amgen Inc.
  • Alexion Pharmaceuticals
  • Hoffmann-La Roche
  • Alexion Pharmaceuticals
  • Amgen Inc.
  • GE Healthcare
  • Ra Pharmaceuticals
  • Regeneron Pharmaceuticals, Inc.
  • Thermo Fisher Scientific Inc.

Adjacent Markets