Protein Expression Systems Market: By System (Yeast Cell Expression Systems, Insect Cell Expression Systems, Prokaryotic Expression Systems, Mammalian Cell Expression Systems, Algal-based Expression Systems, Cell-free Expression Systems), By Applications (Therapeutic Applications, Industrial Application, Research Applications), By Products (Competent Cells, Instruments, Services, Reagents, Expression Vectors), By End-Users (Drug discovery contract research organization, Academics, Pharmaceutical companies), and Geography  

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Protein Expression Systems Market was valued at USD 3,187.8 million in 2022 and is poised to grow at a CAGR of 10.2 % from 2023-2029. The protein expression market refers to the industries that deal with the development of the technologies and products used to express and produce proteins in different biological expression systems. Protein expression systems are a fundamental and vital process in biotechnology and pharmaceutical research, as protein plays a crucial role in several biological functions, understanding disease mechanisms, drugs discovery, diagnostic testing, and therapeutic development. Recombinant proteins are created via protein expression methods, which work by inserting certain DNA sequences into host organisms. Large amounts of proteins may be produced by researchers using these systems for research, characterization, and commercial manufacturing. The market for protein expression systems includes a wide range of technologies, including cell-free, yeast, insect, and mammalian cell expression systems as well as bacterial and yeast expression systems. The increasing demand for recombinant proteins in various research and therapeutic applications coupled with the rising prevalence of chronic diseases is majorly driving the protein expression system market. Moreover, continuous advancements in genetic engineering and biotechnology, the growth of the biopharmaceutical industry, and associated research and development activities, as well as advancements in proteomics research, have led to the development of advanced protein expression systems significantly contribute to the growth of the protein expression systems market. Furthermore, advancements in gene editing technologies and growing demand for biopharmaceuticals such as monoclonal antibodies, recombinant proteins, and therapeutic enzymes, provide significant opportunities for protein expression systems. However, the high costs associated with establishing and maintaining protein expression systems can pose a barrier for the growth of the protein expression systems market. Protein Expression Systems Market players are developing innovative solutions to expand their product portfolios and meet the growing demand for protein expression technologies in various research, diagnostic, and therapeutic applications. For instance, in Mar 2022, ProteoGenix, launched a new XtenCHOTM Transient Chinese Hamster Ovary (CHO) Expression System to improve biologics development.

Protein Expression Systems Market Key Developments:

  • In July 2018, – Polyplus-transfection SA launched FectoCHO Expression System designed for enhanced protein production in CHO cells.

Protein Expression Systems Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

12.5%

Largest Market

Asia Pacific

Fastest Growing Market

Europe
Protein Expression Systems Market Dynamics

Major driving factors for growth of the market include, an increase in R&D activities by many biopharmaceutical, biotechnology, and pharmaceuticals companies to manufacture advanced biologics such as vaccines, monoclonal antibodies, and therapeutic proteins. The expanding biologics market and increasing demand from proteomics market are anticipated to fuel the protein expression systems market. However, stringent government regulations related with protein therapeutics and production of biologics could hamper the growth of the protein expression systems market. The high investment in the R&D activities in the fields of biotechnology and pharmaceutical industry are expected to constrain the growth of protein expression systems market.

Key Features of the Reports

  • The report provides granular level information about the market size, regional market share, historic market (2018-2022) and forecast (2023-2029)
  • The report covers in-detail insights about the competitors overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments and startup's details that are actively working in the market
  • The report provides plethora of information about market entry strategies, regulatory framework, and reimbursement scenario
  • The report analyses the impact of the socio-political environment through PESTLE Analysis and competition through Porter’s Five Force Analysis in addition to recent technology advancements and innovations in the market

Protein Expression Systems Market Segmentation

By System
  • Yeast Cell Expression Systems
  • Insect Cell Expression Systems
  • Prokaryotic Expression Systems
  • Mammalian Cell Expression Systems
  • Algal-based Expression Systems
  • Cell-free Expression Systems
By Applications
  • Therapeutic Applications
  • Industrial Application
  • Research Applications
By Products
  • Competent Cells
  • Instruments
  • Services
  • Reagents
  • Expression Vectors
By End-Users
  • Drug discovery contract research organizations
  • Academics
  • Pharmaceutical companies

Frequently Asked Questions

The protein expression systems market size was valued at USD 3,187.8 million in 2022

Rising R&D Activity in the Pharmaceutical Sector

Europe is the fastest-growing for protein expression systems market

1. Executive Summary
2. Global Protein Expression Systems Market Introduction 
2.1.Global Protein Expression Systems Market  - Taxonomy
2.2.Global Protein Expression Systems Market  - Definitions
2.2.1.System
2.2.2.Applications
2.2.3.Products
2.2.4.End Users
2.2.5.Region
3. Global Protein Expression Systems Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4. Protein Expression Systems Market Analysis, 2018 - 2022 and Forecast 2023 - 2029
4.1.  Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5. Global Protein Expression Systems Market  By System, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
5.1. Yeast Cell Expression Systems
5.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Insect Cell Expression Systems
5.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Prokaryotic Expression Systems
5.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Mammalian Cell Expression Systems
5.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
5.5. Algal-based Expression Systems
5.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.5.3. Market Opportunity Analysis 
5.6. Cell-free Expression Systems
5.6.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
5.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.6.3. Market Opportunity Analysis 
6. Protein Expression Systems Market  By Applications, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
6.1. Therapeutic Applications
6.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Industrial Application
6.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. Research Applications
6.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
7. Global Protein Expression Systems Market  By Products, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
7.1. Competent Cells
7.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Instruments
7.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Services
7.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Reagents
7.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
7.5. Expression Vectors
7.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
7.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.5.3. Market Opportunity Analysis 
8. Global Protein Expression Systems Market  By End Users, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
8.1. Drug discovery contract research organizations
8.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Academics
8.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Pharmaceutical companies
8.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
9. Global Protein Expression Systems Market  By Region, 2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
9.1. North America
9.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
9.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.1.3. Market Opportunity Analysis 
9.2. Europe
9.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
9.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.2.3. Market Opportunity Analysis 
9.3. Asia Pacific (APAC)
9.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
9.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.3.3. Market Opportunity Analysis 
9.4. Middle East and Africa (MEA)
9.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
9.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.4.3. Market Opportunity Analysis 
9.5. Latin America
9.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029, (Sales Value USD Million)
9.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.5.3. Market Opportunity Analysis 
10. North America Protein Expression Systems Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
10.1. System Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Yeast Cell Expression Systems
10.1.2.Insect Cell Expression Systems
10.1.3.Prokaryotic Expression Systems
10.1.4.Mammalian Cell Expression Systems
10.1.5.Algal-based Expression Systems
10.1.6.Cell-free Expression Systems
10.2.  Applications Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Therapeutic Applications
10.2.2.Industrial Application
10.2.3.Research Applications
10.3.  Products Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Competent Cells
10.3.2.Instruments
10.3.3.Services
10.3.4.Reagents
10.3.5.Expression Vectors
10.4.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Drug discovery contract research organizations
10.4.2.Academics
10.4.3.Pharmaceutical companies
10.5.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.5.1.United States of America (USA)
10.5.2.Canada
11. Europe Protein Expression Systems Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
11.1. System Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Yeast Cell Expression Systems
11.1.2.Insect Cell Expression Systems
11.1.3.Prokaryotic Expression Systems
11.1.4.Mammalian Cell Expression Systems
11.1.5.Algal-based Expression Systems
11.1.6.Cell-free Expression Systems
11.2.  Applications Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Therapeutic Applications
11.2.2.Industrial Application
11.2.3.Research Applications
11.3.  Products Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Competent Cells
11.3.2.Instruments
11.3.3.Services
11.3.4.Reagents
11.3.5.Expression Vectors
11.4.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.Drug discovery contract research organizations
11.4.2.Academics
11.4.3.Pharmaceutical companies
11.5.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.5.1.Germany
11.5.2.France
11.5.3.Italy
11.5.4.United Kingdom (UK)
11.5.5.Spain
11.5.6.Rest of EU
11.5.7.
12. Asia Pacific (APAC) Protein Expression Systems Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
12.1. System Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Yeast Cell Expression Systems
12.1.2.Insect Cell Expression Systems
12.1.3.Prokaryotic Expression Systems
12.1.4.Mammalian Cell Expression Systems
12.1.5.Algal-based Expression Systems
12.1.6.Cell-free Expression Systems
12.2.  Applications Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Therapeutic Applications
12.2.2.Industrial Application
12.2.3.Research Applications
12.3.  Products Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Competent Cells
12.3.2.Instruments
12.3.3.Services
12.3.4.Reagents
12.3.5.Expression Vectors
12.4.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.Drug discovery contract research organizations
12.4.2.Academics
12.4.3.Pharmaceutical companies
12.5.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.5.1.China
12.5.2.India
12.5.3.Australia and New Zealand (ANZ)
12.5.4.Japan
12.5.5.Rest of APAC
13. Middle East and Africa (MEA) Protein Expression Systems Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
13.1. System Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Yeast Cell Expression Systems
13.1.2.Insect Cell Expression Systems
13.1.3.Prokaryotic Expression Systems
13.1.4.Mammalian Cell Expression Systems
13.1.5.Algal-based Expression Systems
13.1.6.Cell-free Expression Systems
13.2.  Applications Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Therapeutic Applications
13.2.2.Industrial Application
13.2.3.Research Applications
13.3.  Products Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Competent Cells
13.3.2.Instruments
13.3.3.Services
13.3.4.Reagents
13.3.5.Expression Vectors
13.4.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Drug discovery contract research organizations
13.4.2.Academics
13.4.3.Pharmaceutical companies
13.5.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.5.1.GCC Countries
13.5.2.South Africa
13.5.3.Rest of MEA
14. Latin America Protein Expression Systems Market ,2018 - 2022 and Forecast 2023 - 2029 (Sales Value USD Million)
14.1. System Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.1.1.Yeast Cell Expression Systems
14.1.2.Insect Cell Expression Systems
14.1.3.Prokaryotic Expression Systems
14.1.4.Mammalian Cell Expression Systems
14.1.5.Algal-based Expression Systems
14.1.6.Cell-free Expression Systems
14.2.  Applications Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.2.1.Therapeutic Applications
14.2.2.Industrial Application
14.2.3.Research Applications
14.3.  Products Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.3.1.Competent Cells
14.3.2.Instruments
14.3.3.Services
14.3.4.Reagents
14.3.5.Expression Vectors
14.4.  End Users Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.4.1.Drug discovery contract research organizations
14.4.2.Academics
14.4.3.Pharmaceutical companies
14.5.  Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.5.1.Brazil
14.5.2.Mexico
14.5.3.Rest of LA
15. Competition Landscape
15.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
15.2.1.Bio-Rad Laboratories, Inc. (U.S.)
15.2.2.GenScript Biotech Corporation (China)
15.2.3.Lucigen Corporation (U.S.)
15.2.4.Synthetic Genomics Inc. (U.S.)
15.2.5.Promega Corporation (U.S.)
15.2.6.Merck KGaA (Germany)
15.2.7.Thermo Fisher Scientific Inc. (U.S.)
15.2.8.Becton, Dickinson & Company (U.S.)
16. Research Methodology 
17. Appendix and Abbreviations 
  • Bio-Rad Laboratories, Inc. (U.S.)
  • GenScript Biotech Corporation (China)
  • Lucigen Corporation (U.S.)
  • Synthetic Genomics Inc. (U.S.)
  • Promega Corporation (U.S.)
  • Merck KGaA (Germany)
  • Thermo Fisher Scientific Inc. (U.S.)
  • Becton, Dickinson & Company (U.S.)
  • Agilent Technologies, Inc. (U.S.)
  • QIAGEN N.V. (Netherlands)
  • Takara Bio Inc. (Japan)
  • Lonza Group Ltd. (Switzerland)
  • LifeSensors Inc. (U.S.)
  • Accelagen Inc. (U.S.)
  • Geneva Biotech (Switzerland)
  • Viva Biotech (China)