- In-Vitro Transcription
- In-Vivo Transcription
- Chemical Synthesis
RNA Synthesis Market size was valued at USD 2,153.4 million in 2023 and is poised to grow at a CAGR of 19.9 % from 2024 to 2030. The RNA Synthesis Market is driven by the Growing prevalence of chronic and infectious diseases, the increasing adoption of RNA-based therapies & molecular diagnostics, and the increase in funding in life science, and technological advancements in RNA synthesis methods. However, technological complexity, side effects of mRNA vaccines affecting the RNA synthesis market, and challenges for large-scale manufacturing of mRNA vaccines are the restraints of the market that can hinder market growth and need to be addressed.
Approximately one in three adults worldwide suffer from MCCs. However, there is no universally agreed-upon taxonomy for MCCs, leading to variations in prevalence rates. The global RNA synthesis market presents several opportunities, including the development of new RNA-based therapies, increasing adoption of RNA interference (RNAi), and growing demand for personalized medicine. The global RNA synthesis market is expected to continue to grow in the coming years, driven by the factors mentioned above. Some of the key trends in the market include strategic acquisitions and innovations in RNA synthesis technologies and increasing automation of RNA synthesis workflows, increasing use of RNA synthesis in synthetic biology.
The synergy between the rising demand for RNA-based diagnostics and increasing research funding is creating a fertile ground for the RNA synthesis market. As RNA technologies continue to evolve, we can expect even more innovative diagnostic tools and personalized medicine approaches. This exciting future holds immense potential for improving healthcare outcomes and revolutionizing the way we diagnose and treat diseases.
RNA Synthesis Market Key Developments:
- In September 2022, Thermo Fisher Scientific’s scalable mRNA Production Solutions, utilizing customized Dynabeads. These solutions enable scalable, GMP-grade mRNA synthesis and purification for vaccine research and production
- In Jan 2024, Merck, a leading science and technology company, announced a licensing agreement with Inspirna, Inc. for the first-in-class ompenaclid (rgx-202) currently in phase II development for RAS-mutated advanced or metastatic colorectal cancer, the collaboration includes exclusive license outside US with the option to co-develop and co-promote ompenaclid in US.
RNA Synthesis Market Summary
Study Period
2024 - 2030
Base Year
2023
CAGR
19.9%
Largest Market
North America
Fastest Growing Market
Asia Pacific
RNA Synthesis Market Dynamics
The world of molecular diagnostics is witnessing a significant shift towards RNA (ribonucleic acid). This surge in RNA adoption is driving a parallel growth in the RNA synthesis market, fuelled further by increasing research funding. Traditionally, DNA (deoxyribonucleic acid) has been the king of molecular diagnostics. However, RNA offers unique advantages. It plays a critical role in translating genetic information into proteins, the workhorses of cells. By analysing RNA, researchers can gain insights into cellular activity, disease progression, and even potential drug targets. Techniques like RNA sequencing (RNA-Seq) allow scientists to map an entire cell's RNA profile, providing a deeper understanding of cellular processes. This newfound appreciation for RNA is transforming diagnostics. RT-PCR (reverse transcription polymerase chain reaction), a technique that utilizes RNA synthesis, has been instrumental in the fight against COVID-19. Similarly, RNA-based tests are being developed for various diseases, including cancer and neurological disorders. These tests offer greater sensitivity and specificity compared to traditional methods, leading to earlier and more accurate diagnoses. The increasing adoption of RNA in diagnostics has attracted significant research funding from government agencies, private institutions, and pharmaceutical companies. This funding fuels advancements in RNA synthesis technologies. Companies are developing faster, more efficient, and cost-effective methods for synthesizing high-quality RNA. Additionally, research is ongoing to improve the stability and purity of synthetic RNA, making it even more versatile for diagnostic applications.
North-America Got Significant Share of
RNA Synthesis Market Regional Analysis
Based on regions, the market is segmented into North America, Europe, Asia-Pacific, Latin America, and Middle East and Africa. North America region currently holds the largest market share with 35.5% & a market size of USD 850.6 million, and growing at a CAGR of 19.7%, due to the presence of major pharmaceutical and biotechnology companies (e.g., Pfizer, moderna) with established mRNA vaccine production facilities. Strong government support for research and development in life sciences, high healthcare spending and growing adoption of personalized medicine. Asia Pacific region is experiencing the fastest growth at a CAGR of 21.1% with a market size of 543.4 million USD in 2023 in the RNA Synthesis Market.
Increasing government investments in healthcare infrastructure. Rising prevalence of chronic diseases. Growing awareness about RNA-based therapies. A large patient population creates a significant market potential. Europe is a strong contender, significant market share with established research institutions and pharmaceutical companies. Focus on innovation and development of novel RNA-based therapies. Growing emphasis on personalized medicine is driving market expansion. Latin America & Middle East & Africa, these regions are in the early stages of development. Growth will likely be driven by increasing government initiatives to improve healthcare access, rising disposable incomes, and growing awareness about RNA therapies. Factors affecting regional growth, Stringent regulations can hinder market growth in some regions, and a lack of advanced research facilities and skilled workforce can impede market expansion. favourable reimbursement policies for RNA-based therapies can significantly boost market growth. Overall, the RNA synthesis market is poised for significant growth across all regions. North America will likely remain the leader, but Asia Pacific is expected to witness the fastest expansion.
Latin America
Europe
Asia Pacific
Middle East
North America
Key Features of the Reports
- The report provides granular level information about the market size, regional market share, historic market (2019-2023), and forecast (2024-2030)
- The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and key strategies.
- The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market.
- The report tracks recent innovations, key developments, and start-up details that are actively working in the market.
- The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenarios.
RNA Synthesis Market Segmentation
By Technology
By End User
- Academic Research Institutes
- Biopharmaceutical Companies
- Contract Research Organization
By Geography
- North America
- Europe
- The Asia Pacific
- Latin America
- Latin America
- MEA
Frequently Asked Questions
The RNA synthesis market was valued at USD 2,153.4 million in 2023 and is expected to reach USD 6,403.0 million by 2029, growing at a CAGR of 19.9 %.
The RNA Synthesis Market is driven by the Growing prevalence of chronic and infectious diseases, the increasing adoption of RNA-based therapies & molecular diagnostics, and the increase in funding in life science, and technological advancements in RNA synthesis methods.
Technological complexity, side effects of mRNA vaccines affecting the RNA synthesis market, and challenges for large-scale manufacturing of mRNA vaccines are the restraints of the market.
Market research is segmented based on technology, end-use, and region.
Asai-Pacific is the fastest-growing region in the RNA Synthesis Market.
| 1.Executive Summary |
| 2.Global RNA Synthesis Market Introduction |
| 2.1.Global RNA Synthesis Market - Taxonomy |
| 2.2.Global RNA Synthesis Market - Definitions |
| 2.2.1. Technology |
| 2.2.2.End User |
| 2.2.3.Geography |
| 2.2.4.Region |
| 3.Global RNA Synthesis Market Dynamics |
| 3.1. Drivers |
| 3.2. Restraints |
| 3.3. Opportunities/Unmet Needs of the Market |
| 3.4. Trends |
| 3.5. Product Landscape |
| 3.6. New Product Launches |
| 3.7. Impact of COVID 19 on Market |
| 4.Global RNA Synthesis Market Analysis, 2019 - 2023 and Forecast 2024 - 2030 |
| 4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) |
| 4.3. Market Opportunity Analysis |
| 5.Global RNA Synthesis Market By Technology, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 5.1. In-Vitro Transcription |
| 5.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.1.3. Market Opportunity Analysis |
| 5.2. In-Vivo Transcription |
| 5.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.2.3. Market Opportunity Analysis |
| 5.3. Chemical Synthesis |
| 5.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 5.3.3. Market Opportunity Analysis |
| 6.Global RNA Synthesis Market By End User, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 6.1. Academic Research Institutes |
| 6.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 6.1.3. Market Opportunity Analysis |
| 6.2. Biopharmaceutical Companies |
| 6.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 6.2.3. Market Opportunity Analysis |
| 6.3. Contract Research Organization |
| 6.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 6.3.3. Market Opportunity Analysis |
| 7.Global RNA Synthesis Market By Geography, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 7.1. North America |
| 7.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.1.3. Market Opportunity Analysis |
| 7.2. Europe |
| 7.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.2.3. Market Opportunity Analysis |
| 7.3. The Asia Pacific |
| 7.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.3.3. Market Opportunity Analysis |
| 7.4. Latin America |
| 7.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.4.3. Market Opportunity Analysis |
| 7.5. Latin America |
| 7.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 7.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.5.3. Market Opportunity Analysis |
| 7.6. MEA |
| 7.6.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 7.6.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 7.6.3. Market Opportunity Analysis |
| 8.Global RNA Synthesis Market By Region, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 8.1. North America |
| 8.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.1.3. Market Opportunity Analysis |
| 8.2. Europe |
| 8.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.2.3. Market Opportunity Analysis |
| 8.3. Asia Pacific (APAC) |
| 8.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.3.3. Market Opportunity Analysis |
| 8.4. Middle East and Africa (MEA) |
| 8.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.4.3. Market Opportunity Analysis |
| 8.5. Latin America |
| 8.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million) |
| 8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) |
| 8.5.3. Market Opportunity Analysis |
| 9.North America RNA Synthesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 9.1. Technology Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 9.1.1.In-Vitro Transcription |
| 9.1.2.In-Vivo Transcription |
| 9.1.3.Chemical Synthesis |
| 9.2. End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 9.2.1.Academic Research Institutes |
| 9.2.2.Biopharmaceutical Companies |
| 9.2.3.Contract Research Organization |
| 9.3. Geography Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 9.3.1.North America |
| 9.3.2.Europe |
| 9.3.3.The Asia Pacific |
| 9.3.4.Latin America |
| 9.3.5.Latin America |
| 9.3.6.MEA |
| 9.4. Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 9.4.1.United States of America (USA) |
| 9.4.2.Canada |
| 10.Europe RNA Synthesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 10.1. Technology Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.1.1.In-Vitro Transcription |
| 10.1.2.In-Vivo Transcription |
| 10.1.3.Chemical Synthesis |
| 10.2. End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.2.1.Academic Research Institutes |
| 10.2.2.Biopharmaceutical Companies |
| 10.2.3.Contract Research Organization |
| 10.3. Geography Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.3.1.North America |
| 10.3.2.Europe |
| 10.3.3.The Asia Pacific |
| 10.3.4.Latin America |
| 10.3.5.Latin America |
| 10.3.6.MEA |
| 10.4. Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 10.4.1.Germany |
| 10.4.2.France |
| 10.4.3.Italy |
| 10.4.4.United Kingdom (UK) |
| 10.4.5.Spain |
| 11.Asia Pacific (APAC) RNA Synthesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 11.1. Technology Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.1.1.In-Vitro Transcription |
| 11.1.2.In-Vivo Transcription |
| 11.1.3.Chemical Synthesis |
| 11.2. End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.2.1.Academic Research Institutes |
| 11.2.2.Biopharmaceutical Companies |
| 11.2.3.Contract Research Organization |
| 11.3. Geography Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.3.1.North America |
| 11.3.2.Europe |
| 11.3.3.The Asia Pacific |
| 11.3.4.Latin America |
| 11.3.5.Latin America |
| 11.3.6.MEA |
| 11.4. Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 11.4.1.China |
| 11.4.2.India |
| 11.4.3.Australia and New Zealand (ANZ) |
| 11.4.4.Japan |
| 11.4.5.Rest of APAC |
| 12.Middle East and Africa (MEA) RNA Synthesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 12.1. Technology Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.1.1.In-Vitro Transcription |
| 12.1.2.In-Vivo Transcription |
| 12.1.3.Chemical Synthesis |
| 12.2. End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.2.1.Academic Research Institutes |
| 12.2.2.Biopharmaceutical Companies |
| 12.2.3.Contract Research Organization |
| 12.3. Geography Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.3.1.North America |
| 12.3.2.Europe |
| 12.3.3.The Asia Pacific |
| 12.3.4.Latin America |
| 12.3.5.Latin America |
| 12.3.6.MEA |
| 12.4. Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 12.4.1.GCC Countries |
| 12.4.2.South Africa |
| 12.4.3.Rest of MEA |
| 13.Latin America RNA Synthesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million) |
| 13.1. Technology Analysis and Forecast by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.1.1.In-Vitro Transcription |
| 13.1.2.In-Vivo Transcription |
| 13.1.3.Chemical Synthesis |
| 13.2. End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.2.1.Academic Research Institutes |
| 13.2.2.Biopharmaceutical Companies |
| 13.2.3.Contract Research Organization |
| 13.3. Geography Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.3.1.North America |
| 13.3.2.Europe |
| 13.3.3.The Asia Pacific |
| 13.3.4.Latin America |
| 13.3.5.Latin America |
| 13.3.6.MEA |
| 13.4. Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) |
| 13.4.1.Brazil |
| 13.4.2.Mexico |
| 13.4.3.Rest of LA |
| 14. Competition Landscape |
| 14.1. Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) |
| 14.2.1.Aldevron |
| 14.2.2.Aurigene Pharmaceutical Services |
| 14.2.3.Biomay |
| 14.2.4.Curia |
| 14.2.5.eTheRNA |
| 14.2.6.Eurogentec |
| 14.2.7.Genscript |
| 14.2.8.Merck KGaA |
| 14.2.9.TriLink BioTechnologies |
| 14.2.10.Vernal Biosciences |
| 14.2.11.WuXi Biologics |
| 14.2.12.Maravai LifeSciences |
| 14.2.13.Yeasen Biotechnology (Shanghai) Co., Ltd. |
| 14.2.14.Thermo Fisher Scientific, Inc. |
| 14.2.15.New England Biolabs |
| 15. Research Methodology |
| 16. Appendix and Abbreviations |
- Aldevron
- Aurigene Pharmaceutical Services
- Biomay
- Curia
- eTheRNA
- Eurogentec
- Genscript
- Merck KGaA
- TriLink BioTechnologies
- Vernal Biosciences
- WuXi Biologics
- Maravai LifeSciences
- Yeasen Biotechnology (Shanghai) Co., Ltd.
- Thermo Fisher Scientific, Inc.
- New England Biolabs