Bone Substitute And Allografts Bone Market: By Products (Allografts (Machined Allografts and Demineralized Bone Matrix), Bone Grafts Substitutes (Bone Morphogenic Proteins (BMP) and Synthetic Bone Grafts), and Cell-Based Matrices)), By Application (Craniomaxillofacial, Dental, Foot & Ankle, Joint Reconstruction, Long Bone, and Spinal Fusion) and By Geography  

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The bone substitute and allograft bone market size was valued at USD 3.1 billion in 2022 and growing at a CAGR of 6.1% from 2023 to 2029. The growing use of grafts in dental operations is expected to generate profitable growth prospects for the market players during the forecast period. Rising demand for dental bone grafts and technological advances propel the market forward. Increased investment in R&D by key players in bone grafts and their substitutes and an increase in incidences of orthopedic operations among the elderly are projected to generate significant growth for market players over the forecast period. Introducing novel polymer and ceramic materials with biologically superior features is one of the market's essential developments. New manufacturing technologies like fast prototyping and 3D printing assist in the manufacture of free-form biomaterial scaffolds for tissue regeneration. Furthermore, increased morbidity rates, a growing geriatric population, and an increase in occurrences of osteoarthritis are driving up demand for bone grafts and substitutes. Apart from that, the market is being bolstered by a shift toward minimally invasive procedures and a growing awareness among patients about the benefits of biologic bone regeneration. The availability of improved products in various forms and sizes, the rising frequency of orthopedic difficulties and periodontal disorders, and the growing number of studies examining the enhancement of bioactivity of bone graft substitutes are some of the other growth-inducing aspects. To maintain the market position in the competition, key players worldwide employ various techniques in the bone graft substitutes market. Companies are concentrating on launching sophisticated products and strengthening their distribution channels. Moreover, numerous companies in the global bone graft replacements market are investing in research to develop high-efficiency materials. For instance, in January 2021, Dentsply Sirona acquired Datum Dental Ltd., a company recognized for its unique dental regeneration solutions. Dentsply Sirona promotes the whole OSSIX portfolio in the United States, Canada, and several other countries, including OSSIX Plus, OSSIX Volumax, and OSSIX Bone.

Bone Substitute And Allografts Bone Market Key Developments:
  • In January 2020, Orthopeaditrics Corp. introduced a synthetic bone graft substitute in the United States called QuickPack. It is highly viscous and contains calcium phosphate cement that closely resembles the mineral phase of a bone.
  • In March 2022, Fredun Pharmaceuticals Limited received approval to manufacture Xenografts for various dental and orthopedic surgical appliances from the Central Drugs Standard Control Organisation (COSCO), India.

Bone Substitutes And Allografts Bone Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

6.1%

Largest Market

Europe

Fastest Growing Market

Asia-Pacific
Bone Substitutes And Bone Allografts Market Dynamics

The development of biocompatible synthetic bone grafts, technical improvements for adopting allografts from autografts, and increased demand for dental bone transplants drive the global bone grafts and substitutes market. Bone graft substitutes are gaining popularity as bone graft extenders, particularly posterolateral spinal fusion. As a result, bone graft substitutes for spine fusion procedures have increased dramatically. The worldwide market is predicted to see significant growth due to an increase in spine fusion surgeries. However, higher surgical costs and ethical concerns about bone grafting operations are expected to hinder market expansion for bone grafts and alternatives.

Key Features of the Reports

  • The bone substitute and allograft bone market report provides granular level information about the market size, regional market share, historic market (2018 to 2022) and forecast (2023 to 2029)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments and startup’s details that are actively working in the market
  • The report provides plethora of information about market entry strategies, regulatory framework and reimbursement scenario
  • The report analyses the impact of socio-political environment through PESTLE Analysis and competition through Porter’s Five Force Analysis in addition to recent technology advancements and innovations in the market

Bone Substitutes And Allografts Bone Market Segmentation

By Product Type
  • Allografts
  • Bone Grafts Substitutes
  • Cell-Baseded Matrices
By Application
  • Craniomaxillofacial
  • Dental
  • Foot & Ankle
  • Joint Reconstruction
  • Long Bone
  • Spinal Fusion
By Geography
  • North America,
  • Europe,
  • Asia Pacific,
  • Latin America
  • MEA

Frequently Asked Questions

The bone substitutes and bone allografts market is projected to expand at a CAGR of 6.1% during the forecast period.  

Medtronic, Stryker Corporation, Smith and Nephew Inc, NuVasive, Inc., Wright Medical Group N.V

North America is the fastest-growing region for bone substitutes and the bone allografts market

1. Executive Summary
2. Global Bone Substitutes and Bone Allografts Market Introduction
2.1. Global Bone Substitutes and Bone Allografts Market Taxonomy
2.2. Global Bone Substitutes and Bone Allografts Market Definitions
2.2.1. Product
2.2.2. Application
3. Global Bone Substitutes and Bone Allografts Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Global Bone Substitutes and Bone Allografts Market Dynamic Factors - Impact Analysis
3.6. Global Bone Substitutes and Bone Allografts Market Competition Landscape
4. Global Bone Substitutes and Bone Allografts Market Analysis,2018 - 2022 and Forecast, 2023 - 2029
4.1. Market Analysis,2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
4.2. Year-over-Year (Y-o-Y) Growth Analysis (%)
4.3. Market Opportunity Analysis
5. Global Bone Substitutes and Bone Allografts Market, By Product, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.1. Bone Substitutes
5.1.1. Hydroxyapatites (HAp)
5.1.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.1.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.1.3. Market Opportunity Analysis
5.1.2. Calcium Phosphate
5.1.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.1.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.2.3. Market Opportunity Analysis
5.1.3. Calcium Sulphate
5.1.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.1.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.3.3. Market Opportunity Analysis
5.1.4. Bioactive Glass
5.1.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.1.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.1.4.3. Market Opportunity Analysis
5.2. Bone Allografts
5.2.1. Freeze Dried
5.2.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.2.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.1.3. Market Opportunity Analysis
5.2.2. Demineralized Bone Matrix
5.2.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.2.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.2.3. Market Opportunity Analysis
5.2.3. Tendon Allografts
5.2.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.2.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.3.3. Market Opportunity Analysis
5.2.4. Synthetic Tendon Grafts
5.2.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
5.2.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
5.2.4.3. Market Opportunity Analysis
6. Global Bone Substitutes and Bone Allografts Market, By Application, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.1. Spinal Fusion
6.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.1.3. Market Opportunity Analysis
6.2. Long Bone
6.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.2.3. Market Opportunity Analysis
6.3. Foot and Ankle
6.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.3.3. Market Opportunity Analysis
6.4. Craniomaxillofacial
6.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.4.3. Market Opportunity Analysis
6.5. Joint Reconstruction
6.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.5.3. Market Opportunity Analysis
6.6. Dental Bone Grafting
6.6.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.6.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.6.3. Market Opportunity Analysis
6.7. Others
6.7.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
6.7.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
6.7.3. Market Opportunity Analysis
7. Global Bone Substitutes and Bone Allografts Market Forecast, By Region, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
7.1. North America
7.1.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
7.1.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.1.3. Market Opportunity Analysis
7.2. Europe
7.2.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
7.2.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.2.3. Market Opportunity Analysis
7.3. Asia-Pacific
7.3.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
7.3.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.3.3. Market Opportunity Analysis
7.4. Latin America
7.4.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
7.4.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.4.3. Market Opportunity Analysis
7.5. Middle East and Africa
7.5.1. Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
7.5.2. Year-over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%)
7.5.3. Market Opportunity Analysis
7.6. Global Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By Product, Application and Region, 2023 - 2029
8. North America Bone Substitutes and Bone Allografts MarketAnalysis,2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
8.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
8.1.1. Bone Substitutes
8.1.1.1. Hydroxyapatites (HAp)
8.1.1.2. Calcium Phosphate
8.1.1.3. Calcium Sulphate
8.1.1.4. Bioactive Glass
8.1.2. Bone Allografts
8.1.2.1. Freeze Dried
8.1.2.2. Demineralized Bone Matrix
8.1.2.3. Tendon Allografts
8.1.2.4. Synthetic Tendon Grafts
8.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
8.2.1.1. Spinal Fusion
8.2.1.2. Long Bone
8.2.1.3. Foot and Ankle
8.2.1.4. Craniomaxillofacial
8.2.1.5. Joint Reconstruction
8.2.1.6. Dental Bone Grafting
8.2.1.7. Others
8.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
8.3.1. USA
8.3.2. Canada
8.4. North America Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By  Product, Application, and Country, 2023 - 2029
8.5. North America Bone Substitutes and Bone Allografts Market Dynamics Trends
9. Europe Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
9.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
9.1.1. Bone Substitutes
9.1.1.1. Hydroxyapatites (HAp)
9.1.1.2. Calcium Phosphate
9.1.1.3. Calcium Sulphate
9.1.1.4. Bioactive Glass
9.1.2. Bone Allografts
9.1.2.1. Freeze Dried
9.1.2.2. Demineralized Bone Matrix
9.1.2.3. Tendon Allografts
9.1.2.4. Synthetic Tendon Grafts
9.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
9.2.1.1. Spinal Fusion
9.2.1.2. Long Bone
9.2.1.3. Foot and Ankle
9.2.1.4. Craniomaxillofacial
9.2.1.5. Joint Reconstruction
9.2.1.6. Dental Bone Grafting
9.2.1.7. Others
9.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
9.3.1. Germany
9.3.2. UK
9.3.3. France
9.3.4. Spain
9.3.5. Italy
9.3.6. Russia
9.3.7. Poland
9.3.8. Rest of Europe
9.4. Europe Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By  Product, Application, and Country, 2023 - 2029
9.5. Europe Bone Substitutes and Bone Allografts Market Dynamics Trends
10. Asia-Pacific Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
10.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
10.1.1. Bone Substitutes
10.1.1.1. Hydroxyapatites (HAp)
10.1.1.2. Calcium Phosphate
10.1.1.3. Calcium Sulphate
10.1.1.4. Bioactive Glass
10.1.2. Bone Allografts
10.1.2.1. Freeze Dried
10.1.2.2. Demineralized Bone Matrix
10.1.2.3. Tendon Allografts
10.1.2.4. Synthetic Tendon Grafts
10.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
10.2.1.1. Spinal Fusion
10.2.1.2. Long Bone
10.2.1.3. Foot and Ankle
10.2.1.4. Craniomaxillofacial
10.2.1.5. Joint Reconstruction
10.2.1.6. Dental Bone Grafting
10.2.1.7. Others
10.3. Country Analysis2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
10.3.1. Japan
10.3.2. China
10.3.3. India
10.3.4. ASEAN
10.3.5. Australia & New Zealand
10.3.6. Rest of Asia-Pacific
10.4. Asia-Pacific Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By  Product, Application, and Country, 2023 - 2029
10.5. Asia-Pacific Bone Substitutes and Bone Allografts Market Dynamics Trends
11. Latin America Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
11.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
11.1.1. Bone Substitutes
11.1.1.1. Hydroxyapatites (HAp)
11.1.1.2. Calcium Phosphate
11.1.1.3. Calcium Sulphate
11.1.1.4. Bioactive Glass
11.1.2. Bone Allografts
11.1.2.1. Freeze Dried
11.1.2.2. Demineralized Bone Matrix
11.1.2.3. Tendon Allografts
11.1.2.4. Synthetic Tendon Grafts
11.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
11.2.1.1. Spinal Fusion
11.2.1.2. Long Bone
11.2.1.3. Foot and Ankle
11.2.1.4. Craniomaxillofacial
11.2.1.5. Joint Reconstruction
11.2.1.6. Dental Bone Grafting
11.2.1.7. Others
11.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
11.3.1. Brazil
11.3.2. Mexico
11.3.3. Argentina
11.3.4. Rest of Latin America
11.4. Latin America Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By  Product, Application, and Country, 2023 - 2029
11.5. Latin America Bone Substitutes and Bone Allografts Market Dynamics Trends
12. Middle East and Africa Bone Substitutes and Bone Allografts Market Analysis, 2018 - 2022 and Forecast, 2023 - 2029 (Revenue, USD Mn)
12.1. By Product Analysis 2018 - 2022 and Forecast 2023 - 2029by Revenue (USD Mn),Y-o-Y Growth (%), and Market Share (%)
12.1.1. Bone Substitutes
12.1.1.1. Hydroxyapatites (HAp)
12.1.1.2. Calcium Phosphate
12.1.1.3. Calcium Sulphate
12.1.1.4. Bioactive Glass
12.1.2. Bone Allografts
12.1.2.1. Freeze Dried
12.1.2.2. Demineralized Bone Matrix
12.1.2.3. Tendon Allografts
12.1.2.4. Synthetic Tendon Grafts
12.2. Application Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn), Y-o-Y Growth (%) and Market Share (%)
12.2.1.1. Spinal Fusion
12.2.1.2. Long Bone
12.2.1.3. Foot and Ankle
12.2.1.4. Craniomaxillofacial
12.2.1.5. Joint Reconstruction
12.2.1.6. Dental Bone Grafting
12.2.1.7. Others
12.3. Country Analysis 2018 - 2022 and Forecast 2023 - 2029 by Revenue (USD Mn) Y-o-Y Growth (%) and Market Share (%)
12.3.1. Gulf Cooperation Council (GCC) Countries
12.3.2. Israel
12.3.3. South Africa
12.3.4. Rest of MEA
12.4. MEA Bone Substitutes and Bone Allografts Market - Opportunity Analysis Index, By  Product, Application, and Country, 2023 - 2029
12.5. MEA Bone Substitutes and Bone Allografts Market Dynamics Trends
13. Competition Landscape
13.1. Strategic Dashboard of Top Market Players
13.2. Company Profiles (Introduction, Financial Analysis, Technology & Service Offerings, Key Developments, Strategies, and SWOT Analysis)
13.2.1. AlloSource
13.2.2. Baxter
13.2.3. DEPUY SYNTHES
13.2.4. INTEGRA LIFESCIENCES HOLDINGS CORPORATION
13.2.5. Medtronic
13.2.6. NuVasive, Inc.
13.2.7. Orthovita, Inc.
13.2.8. Smith and Nephew Inc.
13.2.9. Stryker Corporation
13.2.10. Wright Medical Group N.V
13.2.11. ZIMMER BIOMET
14. Research Methodology
15. Key Assumptions and Acronyms
  • AlloSource
  • DePuySynthes, Inc.
  • Baxter
  • Nuvasive, Inc.
  • Smith & Nephew
  • Medtronic
  • Orthofix Holdings, Inc.
  • TBF Tissue Engineering
  • OST Development
  • Zimmer Biomet
  • Wright Medical Group N.V.

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