Bone Grafts Market Size, Share, Growth, Trends, and Global Industry Analysis: By Material (Natural (Allograft, Allografts), Synthetic (Ceramic, Composite, Polymer, Bone Morphogenetic Proteins)), By Application (Craniomaxillofacial, Dental, Foot and Ankle, Joint Reconstruction, Long Bone Spinal Fusion), By End-User (Hospitals, Ambulatory Surgical Centers, Dental Clinics) and Region Forecast 2020-2031  

Bone grafts market size was valued at US$ 3.4 billion in 2024 and is expected to reach US$ 5.1 billion by 2031, growing at a significant CAGR of 6.1% from 2025-2031. Bone grafting is a surgical procedure used to fix bones or joints. Bone grafting is the replacement or repair of bones that are damaged due to trauma or fractures with the bones from other body tissue. For instance, in lumbar surgery, a bone from the donor site is transplanted to the recipient site to facilitate the fusion of vertebrae. The grafting tissue is necessary for osteoinduction, a natural bone healing process. Bone grafts are of three types autologous, allograft, and Synthetic bone. Autologous bone is harvested from the patient's own body, often from the iliac crest. Sallograft is cadaveric bone usually obtained from a bone bank.

Synthetic bone made of hydroxyapatite or other naturally occurring, biocompatible substances. Bone grafts have a wide range of applications in sports, trauma plastic, facial, and spinal surgery. The market is expected to grow at a steady state during the forecasting period. Companies focusing on product innovations and line extensions to increase their bone grafts market share. The increasing geriatric population and growing prevalence of bone and joint disorders are the main factors boosting the market growth. According to the National Osteoporosis Foundation (NOF), it is expected that the number of cases of osteoporosis will exceed 61 Mn by 2020. According to the National Spinal Cord Injury Centre in the U.S., Researchers have assessed that in 2015, nearly 12,500 new spinal cord injuries occurred in the year. However, larger players in the market are funding bone graft research, collaborating, and acquiring smaller players to increase their market share.  

Key Developments:

• In April 2025, Xtant Medical Holdings, Inc., a global medical technology company specializing in surgical solutions for spinal, orthopedic, and wound care disorders, announced the launch of Trivium™, a next-generation demineralized bone matrix (DBM) allograft. Featuring advanced PureLoc™ Fiber Technology, Trivium integrates three synergistic elements to deliver superior structure, handling, and biological activity, aiming to set a new standard in bone grafting procedures.
• In February 2025, Evergen, a leading CDMO in regenerative medicine, launched an AI-powered image processing software to enhance the analysis of CT bone graft scans. Unlike traditional methods requiring multiple technicians for subjective assessments, the new system can analyze hundreds of images and generate reports in under 10 seconds. By improving efficiency in bone processing, the technology aims to help more patients access life-changing treatments. .
• In February 2025, the Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) launched two innovative drug-eluting bone graft products, CASPRO and BONYX. Developed by the institute’s Biomedical Technology Wing and commercialized by Onyx Medicals Pvt Ltd, Meerut, the products were unveiled by SCTIMST President S. Kris Gopalakrishnan.