Plasmid DNA Preparation Market: By Product Type, By Application, By End User and Region Forecast 2019-2030  

Plasmid DNA Preparation Market Size, Share, Growth, Trends, and Global Industry Analysis: By Product Type (Research Grade Plasmid DNA Preparation, Industrial Grade Plasmid DNA Preparation, Pre-clinical Grade Plasmid DNA Preparation, GLP Plasmid DNA Preparation, Others), By Application (Gene Therapy, Cell Therapy, Vaccinology, Clinical Research, Others), By End User (Pharmaceutical and Biopharmaceutical Companies, CROs and CMOs, Academic and Research Institutes) and Region Forecast 2019-2030  

Plasmid DNA Preparation Market size was valued at US$ 1,734.7 million in 2023 and is projected to reach US$ 4,261.4 million by 2030 at a CAGR of 13.7% from 2024-2030. the forecast years to reach The market is driven by several factors such as increasing demand for plasmid DNA (pDNA) in cell and gene therapy, rising prevalence of chronic diseases, technological advancements, and growing government support.

pDNA is a crucial component in cell and gene therapies, which are rapidly emerging as promising treatments for a wide range of diseases, and this is fueling the demand for pDNA preparation kits and services, also the growing prevalence of chronic diseases like cancer, neurological disorders, and genetic diseases is leading to an increased need for novel therapeutic approaches, including gene therapy, this in turn is driving the demand for pDNA. Advancements in plasmid manufacturing technologies, such as automation and continuous processing, are making pDNA production faster, more efficient, and cost-effective, this is making pDNA-based therapies more accessible to patients.

Additionally, the governments around the world are increasingly recognizing the potential of gene therapy and are providing funding for research and development in this fiel and this is creating a favorable environment for the growth of the market. The opportunities in the market are significant such as development of novel plasmid delivery systems, growing adoption of personalized medicine, and increasing focus on emerging markets. Increasing Demand for GMP-grade plasmid DNA, growing adoption of single-use technologies, and automation and continuous processing are the trends in the market. However, the constraints in the market will hinder the market growth such as stringent regulatory requirements, high cost of plasmid DNA manufacturing, and lack of skilled workforce.

Plasmid DNA Preparation Market Key Developments

  • In November 2023, Ajinomoto Co., Inc. announced its decision to acquire all units of Forge Biologics Holdings, LLC, a US-based gene therapy Contract Development and Manufacturing Organization (CDMO), for approximately US$ 554 million. This acquisition was part of Ajinomoto’s strategic growth plan in the healthcare sector, leveraging its proprietary “AminoScience” platform. The acquisition aimed to accelerate growth through expansion into gene therapy CDMO, among other areas.
  • In June 2021, Charles River Laboratories International, Inc. completed the acquisition of Vigene Biosciences, Inc. The acquisition was aimed at enhancing Charles River’s gene therapy capabilities, particularly in the high-growth cell and gene therapy CDMO sector.

Plasmid Dna Preparation Market Summary

Study Period

2024 - 2030

Base Year

2023

CAGR

13.7%

Largest Market

North America

Fastest Growing Market

Asia Pacific

Plasmid DNA Preparation Market Dynamics

The Plasmid DNA Preparation Market is growing due to the development of novel plasmid delivery systems that are more efficient and less toxic could open up new opportunities for pDNA-based therapies and personalized medicine is an approach to healthcare that takes into account individual differences in genes, environment, and lifestyle. pDNA can be used to develop personalized therapies for a wide range of diseases. Also, the demand for pDNA is expected to grow in emerging markets such as China and India, this presents a significant opening for manufacturers of pDNA preparation kits and services. Single-use technologies are becoming increasingly popular in the biopharmaceutical industry, as they offer a number of advantages, such as reduced risk of contamination and improved process efficiency. The adoption of single-use technologies is expected to grow in the markets. Automation and continuous processing are being increasingly adopted in the market. These technologies can help to improve the efficiency and scalability of pDNA production.

Plasmid Dna Preparation Market Segmentation Analysis

Report Benchmarks

Details

Report Study Period

2024 - 2030

Market Size in 2023

US$ 1,734.7 million

Market Size in 2030

US$ 4,261.4 million

Market CAGR

13.7%

By Product Type

  • Research Grade Plasmid DNA Preparation,
  • Industrial Grade Plasmid DNA Preparation,
  • Pre-clinical Grade Plasmid DNA Preparation,
  • GLP Plasmid DNA Preparation,
  • Others

By Application

  • Gene Therapy,
  •  Cell Therapy,
  • Vaccinology,
  • Clinical Research,
  • Others

By End User

  • Pharmaceutical and Biopharmaceutical Companies,
  • CROs
  • CMOs
  • Academic and Research Institutes

By Region

  • North America (U.S., Canada)
  • Europe (Germany, U.K., France, Italy, Russia, Spain, Rest of Europe)
  • Asia-Pacific (China, India, Japan, Australia, Southeast Asia, Rest of Asia Pacific)
  • Latin America (Mexico, Brazil, Argentina, Columbia, Rest of Latin America)
  • Middle East & Africa (GCC, Egypt, Nigeria, South Africa, Rest of Middle East and Africa)

Key Features of the Report

  • The plasmid dna preparation market  report provides granular level information about the Market size, regional Market share, historic Market (2019-2023), and forecast (2024-2030)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key Market developments, and key strategies.
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the Market.
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the Market.
  • The report provides a plethora of information about Market entry strategies, regulatory framework, and reimbursement scenarios.
  • The report analyses the impact of the socio-political environment through PESTLE Analysis and competition through Porter's Five Force Analysis.

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Frequently Asked Questions

The plasmid DNA preparation market size was valued at US$ 1,734.7 million in 2023 and is set to reach US$ 4,261.4 million by 2030 at a CAGR of 13.7% from 2024-2030

A plasmid is a circular DNA molecule that exists independently of the bacterial chromosome. It is physically separate from chromosomal DNA and can replicate autonomously within a cell.

• Increasing demand for plasmid DNA (pDNA) in cell and gene therapy
• Rising prevalence of chronic diseases
• Technological advancements
• Growing government support

• Development of novel plasmid delivery systems
• Growing adoption of personalized medicine
• Increasing focus on emerging markets

• Growing adoption of single-use technologies
• Demand for GMP-grade plasmid DNA
• Automation and continuous processing

• Pharmaceutical and Biopharmaceutical Companies
• CROs and CMOs
• Academic and Research Institutes

Author image

Author

Muni Kumar Meravath

Muni Kumar Meravath is a seasoned Healthcare Market Research Analyst with over 6 years of experience in the healthc.....

1.Executive Summary
2.Global Plasmid DNA Preparation Market Introduction 
2.1.Global Plasmid DNA Preparation Market  - Taxonomy
2.2.Global Plasmid DNA Preparation Market  - Definitions
2.2.1. By Product Type 
2.2.2. By Application
2.2.3. By End User
2.2.4. By Region
3.Global Plasmid DNA Preparation Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Plasmid DNA Preparation Market Analysis, 2019 - 2023 and Forecast 2024 - 2030
4.1.  Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Plasmid DNA Preparation Market  By Product Type , 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
5.1. Research Grade Plasmid DNA Preparation,
5.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Industrial Grade Plasmid DNA Preparation,
5.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Pre-clinical Grade Plasmid DNA Preparation,
5.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. GLP Plasmid DNA Preparation,
5.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
5.5. Others
5.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.5.3. Market Opportunity Analysis 
6.Global Plasmid DNA Preparation Market  By Application, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
6.1. Gene Therapy,
6.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2.  Cell Therapy,
6.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
6.3. Vaccinology,
6.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.3.3. Market Opportunity Analysis 
6.4. Clinical Research,
6.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.4.3. Market Opportunity Analysis 
6.5. Others
6.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.5.3. Market Opportunity Analysis 
7.Global Plasmid DNA Preparation Market  By End User, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
7.1. Pharmaceutical and Biopharmaceutical Companies,
7.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. CROs and
7.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. CMOs,
7.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Academic and Research Institutes
7.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
8.Global Plasmid DNA Preparation Market  By Region, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
8.1. North America
8.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Europe
8.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Asia Pacific (APAC)
8.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
8.4. Middle East and Africa (MEA)
8.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.4.3. Market Opportunity Analysis 
8.5. Latin America
8.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.5.3. Market Opportunity Analysis 
9.North America Plasmid DNA Preparation Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
9.1. Product Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.1.1.Research Grade Plasmid DNA Preparation,
9.1.2.Industrial Grade Plasmid DNA Preparation,
9.1.3.Pre-clinical Grade Plasmid DNA Preparation,
9.1.4.GLP Plasmid DNA Preparation,
9.1.5.Others
9.2.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.2.1.Gene Therapy,
9.2.2. Cell Therapy,
9.2.3.Vaccinology,
9.2.4.Clinical Research,
9.2.5.Others
9.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.3.1.Pharmaceutical and Biopharmaceutical Companies,
9.3.2.CROs and
9.3.3.CMOs,
9.3.4.Academic and Research Institutes
9.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
9.4.1.United States of America (USA)
9.4.2.Canada
10.Europe Plasmid DNA Preparation Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
10.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Research Grade Plasmid DNA Preparation,
10.1.2.Industrial Grade Plasmid DNA Preparation,
10.1.3.Pre-clinical Grade Plasmid DNA Preparation,
10.1.4.GLP Plasmid DNA Preparation,
10.1.5.Others
10.2.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Gene Therapy,
10.2.2. Cell Therapy,
10.2.3.Vaccinology,
10.2.4.Clinical Research,
10.2.5.Others
10.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Pharmaceutical and Biopharmaceutical Companies,
10.3.2.CROs and
10.3.3.CMOs,
10.3.4.Academic and Research Institutes
10.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Germany
10.4.2.France
10.4.3.Italy
10.4.4.United Kingdom (UK)
10.4.5.Spain
11.Asia Pacific (APAC) Plasmid DNA Preparation Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
11.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Research Grade Plasmid DNA Preparation,
11.1.2.Industrial Grade Plasmid DNA Preparation,
11.1.3.Pre-clinical Grade Plasmid DNA Preparation,
11.1.4.GLP Plasmid DNA Preparation,
11.1.5.Others
11.2.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Gene Therapy,
11.2.2. Cell Therapy,
11.2.3.Vaccinology,
11.2.4.Clinical Research,
11.2.5.Others
11.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Pharmaceutical and Biopharmaceutical Companies,
11.3.2.CROs and
11.3.3.CMOs,
11.3.4.Academic and Research Institutes
11.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.China
11.4.2.India
11.4.3.Australia and New Zealand (ANZ)
11.4.4.Japan
11.4.5.Rest of APAC
12.Middle East and Africa (MEA) Plasmid DNA Preparation Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
12.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Research Grade Plasmid DNA Preparation,
12.1.2.Industrial Grade Plasmid DNA Preparation,
12.1.3.Pre-clinical Grade Plasmid DNA Preparation,
12.1.4.GLP Plasmid DNA Preparation,
12.1.5.Others
12.2.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Gene Therapy,
12.2.2. Cell Therapy,
12.2.3.Vaccinology,
12.2.4.Clinical Research,
12.2.5.Others
12.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Pharmaceutical and Biopharmaceutical Companies,
12.3.2.CROs and
12.3.3.CMOs,
12.3.4.Academic and Research Institutes
12.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.GCC Countries
12.4.2.South Africa
12.4.3.Rest of MEA
13.Latin America Plasmid DNA Preparation Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
13.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Research Grade Plasmid DNA Preparation,
13.1.2.Industrial Grade Plasmid DNA Preparation,
13.1.3.Pre-clinical Grade Plasmid DNA Preparation,
13.1.4.GLP Plasmid DNA Preparation,
13.1.5.Others
13.2.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Gene Therapy,
13.2.2. Cell Therapy,
13.2.3.Vaccinology,
13.2.4.Clinical Research,
13.2.5.Others
13.3.  End User Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Pharmaceutical and Biopharmaceutical Companies,
13.3.2.CROs and
13.3.3.CMOs,
13.3.4.Academic and Research Institutes
13.4.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Brazil
13.4.2.Mexico
13.4.3.Rest of LA
14. Competition Landscape
14.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
14.2.1.Merck KGaA
14.2.2.Cobra Biologics Ltd.
14.2.3.GenScript
14.2.4.VGXI, Inc.
14.2.5.Aldevron LLC
14.2.6.Synbio Technologies
14.2.7.Creative Biogene
14.2.8.Vigene Biosciences
14.2.9.Genewiz
15. Research Methodology 
16. Appendix and Abbreviations 

Key Market Players

  • Merck KGaA
  • Cobra Biologics Ltd.
  • GenScript
  • VGXI, Inc.
  • Aldevron LLC
  • Synbio Technologies
  • Creative Biogene
  • Vigene Biosciences
  • Genewiz

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