Cloning And Mutagenesis Market: By Product Type, By Gene Type, By Technique, By Application And Geography

Cloning And Mutagenesis Market Size, Share, Growth, Trends, and Global Industry Analysis: By Product Type (Cloning Kits, Mutagenesis Kits, Vectors, and Others), By Gene Type (Standard Gene, Complex Gene), By Technique (Topo PCR Cloning, Blunt End Cloning, Seamless Cloning, Site-Directed Mutagenesis, and Others), By Application (Protein Engineering, Gene Expression, Gene Therapy, Vaccine Research, and Others) And Region

Cloning And Mutagenesis Market size was valued at US$ 2,438.5 million in 2023 and is poised to grow at a CAGR of 19.3% from 2024-2030. Cloning and mutagenesis are fundamental techniques in molecular biology used to manipulate and study genes and DNA sequences. Cloning in molecular biology refers to the process of making identical copies of a DNA sequence, typically a gene or a piece of DNA, and then propagating these copies in a host organism. Mutagenesis involves deliberately inducing mutations in DNA sequences to study gene function. Continuous advancements in genomic technologies, the increasing prevalence of genetic diseases, the rise of personalized medicine, and the acceptance of genetically modified organisms (GMOs) are the main drivers of the market. According to the Canter for Drug Evaluation and Research (CDER), instance for personalized medicine, the Food and Drug Administration approved 37 new molecular entities (NMEs) in 2022. 12 of them were classified as personalized medicines.

Moreover, Ethical considerations regarding genetic manipulation and regulatory frameworks governing the use of genetically modified organisms (GMOs) pose challenges. Additionally, high technical complexity, the need for skilled personnel, and high costs associated with advanced cloning and mutagenesis technologies are also restraints for the market. The COVID-19 pandemic significantly impacted the Cloning and Mutagenesis Market by accelerating the demand for genomic research and sequencing. Cloning and mutagenesis were crucial in the rapid development of COVID-19 vaccines. For instance, the mRNA vaccines by Pfizer-BioNTech and Moderna involved cloning viral genes to produce spike proteins. Increasing adoption of CRISPR/Cas9 systems and growing interest in personalized therapies based on genetic profiles are some of the main opportunities Increasing automation and development of high-throughput cloning and mutagenesis systems, use cases such as bioremediation and sustainable agriculture are considered as main trends

Cloning And Mutagenesis Market Key Developments:
  • On February 5, 2024—Takara Bio USA, Inc. launched two critical solutions for oncology research. These automated single-cell total RNA-seq (Shasta Total RNA-Seq Kit) and DNA-seq (Shasta Whole-Genome Amplification Kit) library preparation kits will provide high sample and cell throughput, less hands-on time, and the ability to capture more information than other available technologies.
  • In October 2022, iNtRON Biotechnology, a South Korea-based biotech company, introduced its 2nd generation Robot Bacteriophage technology. This technology utilizes random transposon mutagenesis to modify the bacteriophage genome, enabling the identification and removal of non-essential genes.

Cloning And Mutagenesis Market Summary

Study Period

2024-2030

Base Year

2023

CAGR

19.3%

Largest Market

North America

Fastest Growing Market

Asia Pacific

Cloning And Mutagenesis Market Dynamics

According to the FDA, there are 13 GMOs available in the market, and still, several in the developmental stages. Adding to that, approximately 1 in 50 people are affected by a known single-gene disorder, while around 1 in 263 are affected by a chromosomal disorder. The World Health Organization estimates that 10 out of every 1000 people worldwide are affected by genetic disorders, which means that between 70 million and 80 million people are living with one of these diseases. The increased prevalence of genetic disorders leads to the rise of personalized medicine such as gene therapies, thus giving rise to an expansion of the cloning and mutagenesis market. The rise in protein engineering outcomes has significantly increased the drive for cloning and mutagenesis kits, for instance, the FDA has approved more than 200 proteins and peptide-based drugs. The increased prevalence of CRISPR, and NGS with its simplicity, cost-effectiveness, and versatility have revolutionized genetic research and driven demand for cloning and mutagenesis products. The pandemic led to increased funding and global collaboration in genomic research initiatives. Governments, research institutions, and private companies have invested in genomic infrastructure and projects, driving the demand for cloning and mutagenesis products.

Cloning And Mutagenesis Market Segmentation Analysis

Report Benchmarks

Details

Report Study Period

2024-2030

Market Size in 2023

US$ 2,438.5 million

Market CAGR

19.3%

By Product Type

  • Cloning Kits
  • Mutagenesis Kits
  • Vectors
  • Others

By Gene Type

  • Standard Gene
  • Complex Gene

By Application

  • Protein Engineering
  • Gene Expression
  • Gene Therapy
  • Vaccine Research

By End Users

  • Research Organizations
  • Biotech/ Pharmaceutical Companies
  • Contract research organizations (CROs)

Key Features of the Report

  • The report provides granular level information about the market size, regional market share, historic market (2019-2023), and forecast (2024-2030).
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and their key strategies.
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market.
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market.
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenarios.

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Frequently Asked Questions

Cloning And Mutagenesis Market size was valued at US$ 2,438.5 million in 2023 and is poised to grow at a CAGR of 19.3% from 2024-2030.

Major companies operating within the Cloning And Mutagenesis Market are Takara Bio Inc.; Agilent Technologies, Inc.; Thermo Fisher Scientific, Inc.; and New England Biolabs.; Merck KGaA; Promega Corporation, Bio-Rad Laboratories.

Continuous advancements in genomic technologies such as CRISPR, the increasing prevalence of genetic diseases, the rise of personalized medicine, and the acceptance of genetically modified organisms (GMOs) are the main drivers of the market.

North America, particularly the United States, leads in the Cloning And Mutagenesis Market due to the adoption of advanced genetic engineering technologies, including CRISPR/Cas9 and next-generation sequencing, and the presence of research institutions, universities, and biotechnology companies with significant investments in R&D activities

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Author

Muni Kumar Meravath

Muni Kumar Meravath is a seasoned Healthcare Market Research Analyst with over 6 years of experience in the healthc.....

1.Executive Summary
2.Global Cloning And Mutagenesis Market Introduction 
2.1.Global Cloning And Mutagenesis Market  - Taxonomy
2.2.Global Cloning And Mutagenesis Market  - Definitions
2.2.1.Product Type 
2.2.2.Gene Type 
2.2.3.Application
2.2.4.End Users
2.2.5.Region
3.Global Cloning And Mutagenesis Market Dynamics
3.1. Drivers
3.2. Restraints
3.3. Opportunities/Unmet Needs of the Market
3.4. Trends
3.5. Product Landscape
3.6. New Product Launches
3.7. Impact of COVID 19 on Market
4.Global Cloning And Mutagenesis Market Analysis, 2019 - 2023 and Forecast 2024 - 2030
4.1.  Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
4.2.  Year-Over-Year (Y-o-Y) Growth Analysis (%) 
4.3.  Market Opportunity Analysis 
5.Global Cloning And Mutagenesis Market  By Product Type , 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
5.1. Cloning Kits
5.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.1.3. Market Opportunity Analysis 
5.2. Mutagenesis Kits
5.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.2.3. Market Opportunity Analysis 
5.3. Vectors
5.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.3.3. Market Opportunity Analysis 
5.4. Others
5.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
5.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
5.4.3. Market Opportunity Analysis 
6.Global Cloning And Mutagenesis Market  By Gene Type , 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
6.1. Standard Gene
6.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.1.3. Market Opportunity Analysis 
6.2. Complex Gene
6.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
6.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
6.2.3. Market Opportunity Analysis 
7.Global Cloning And Mutagenesis Market  By Application, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
7.1. Protein Engineering
7.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.1.3. Market Opportunity Analysis 
7.2. Gene Expression
7.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.2.3. Market Opportunity Analysis 
7.3. Gene Therapy
7.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.3.3. Market Opportunity Analysis 
7.4. Vaccine Research
7.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
7.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
7.4.3. Market Opportunity Analysis 
8.Global Cloning And Mutagenesis Market  By End Users, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
8.1. Research Organizations
8.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.1.3. Market Opportunity Analysis 
8.2. Biotech/ Pharmaceutical Companies
8.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.2.3. Market Opportunity Analysis 
8.3. Contract research organizations (CROs)
8.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
8.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
8.3.3. Market Opportunity Analysis 
9.Global Cloning And Mutagenesis Market  By Region, 2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
9.1. North America
9.1.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
9.1.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.1.3. Market Opportunity Analysis 
9.2. Europe
9.2.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
9.2.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.2.3. Market Opportunity Analysis 
9.3. Asia Pacific (APAC)
9.3.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
9.3.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.3.3. Market Opportunity Analysis 
9.4. Middle East and Africa (MEA)
9.4.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
9.4.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.4.3. Market Opportunity Analysis 
9.5. Latin America
9.5.1. Market Analysis, 2019 - 2023 and Forecast, 2024 - 2030, (Sales Value USD Million)
9.5.2. Year-Over-Year (Y-o-Y) Growth Analysis (%) and Market Share Analysis (%) 
9.5.3. Market Opportunity Analysis 
10.North America Cloning And Mutagenesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
10.1. Product Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.1.1.Cloning Kits
10.1.2.Mutagenesis Kits
10.1.3.Vectors
10.1.4.Others
10.2.  Gene Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.2.1.Standard Gene
10.2.2.Complex Gene
10.3.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.3.1.Protein Engineering
10.3.2.Gene Expression
10.3.3.Gene Therapy
10.3.4.Vaccine Research
10.4.  End Users Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.4.1.Research Organizations
10.4.2.Biotech/ Pharmaceutical Companies
10.4.3.Contract research organizations (CROs)
10.5.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
10.5.1.United States of America (USA)
10.5.2.Canada
11.Europe Cloning And Mutagenesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
11.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.1.1.Cloning Kits
11.1.2.Mutagenesis Kits
11.1.3.Vectors
11.1.4.Others
11.2.  Gene Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.2.1.Standard Gene
11.2.2.Complex Gene
11.3.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.3.1.Protein Engineering
11.3.2.Gene Expression
11.3.3.Gene Therapy
11.3.4.Vaccine Research
11.4.  End Users Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.4.1.Research Organizations
11.4.2.Biotech/ Pharmaceutical Companies
11.4.3.Contract research organizations (CROs)
11.5.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
11.5.1.Germany
11.5.2.France
11.5.3.Italy
11.5.4.United Kingdom (UK)
11.5.5.Spain
12.Asia Pacific (APAC) Cloning And Mutagenesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
12.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.1.1.Cloning Kits
12.1.2.Mutagenesis Kits
12.1.3.Vectors
12.1.4.Others
12.2.  Gene Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.2.1.Standard Gene
12.2.2.Complex Gene
12.3.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.3.1.Protein Engineering
12.3.2.Gene Expression
12.3.3.Gene Therapy
12.3.4.Vaccine Research
12.4.  End Users Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.4.1.Research Organizations
12.4.2.Biotech/ Pharmaceutical Companies
12.4.3.Contract research organizations (CROs)
12.5.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
12.5.1.China
12.5.2.India
12.5.3.Australia and New Zealand (ANZ)
12.5.4.Japan
12.5.5.Rest of APAC
13.Middle East and Africa (MEA) Cloning And Mutagenesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
13.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.1.1.Cloning Kits
13.1.2.Mutagenesis Kits
13.1.3.Vectors
13.1.4.Others
13.2.  Gene Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.2.1.Standard Gene
13.2.2.Complex Gene
13.3.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.3.1.Protein Engineering
13.3.2.Gene Expression
13.3.3.Gene Therapy
13.3.4.Vaccine Research
13.4.  End Users Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.4.1.Research Organizations
13.4.2.Biotech/ Pharmaceutical Companies
13.4.3.Contract research organizations (CROs)
13.5.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
13.5.1.GCC Countries
13.5.2.South Africa
13.5.3.Rest of MEA
14.Latin America Cloning And Mutagenesis Market ,2019 - 2023 and Forecast 2024 - 2030 (Sales Value USD Million)
14.1. Product Type  Analysis  and Forecast  by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.1.1.Cloning Kits
14.1.2.Mutagenesis Kits
14.1.3.Vectors
14.1.4.Others
14.2.  Gene Type  Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.2.1.Standard Gene
14.2.2.Complex Gene
14.3.  Application Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.3.1.Protein Engineering
14.3.2.Gene Expression
14.3.3.Gene Therapy
14.3.4.Vaccine Research
14.4.  End Users Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.4.1.Research Organizations
14.4.2.Biotech/ Pharmaceutical Companies
14.4.3.Contract research organizations (CROs)
14.5.  Country Analysis 2019 - 2023 and Forecast 2024 - 2030 by Sales Value USD Million, Y-o-Y Growth (%), and Market Share (%) 
14.5.1.Brazil
14.5.2.Mexico
14.5.3.Rest of LA
15. Competition Landscape
15.1.  Market Player Profiles (Introduction, Brand/Product Sales, Financial Analysis, Product Offerings, Key Developments, Collaborations, M & A, Strategies, and SWOT Analysis) 
15.2.1.Agilent Technologies, Inc.
15.2.2.Biorad
15.2.3.ABM Inc.
15.2.4.Cellecta Inc.
15.2.5.Charles River laboratories
15.2.6.Codex DNA Inc.
15.2.7.Creative Biogene
15.2.8.Eurofins Scientific
15.2.9.EZBioscience
15.2.10.GENEWIZ Inc.
15.2.11.GenScript
15.2.12.Gene2Me
15.2.13.iNtRON
15.2.14.Jena Bioscience GmbH
15.2.15.Lonza
15.2.16.Macrogen Inc
15.2.17.MerckKGaA
15.2.18.New England Biolabs
15.2.19.Sartorius AG
15.2.20.Takara Bio Inc.
15.2.21.Thermo Fisher Scientific Inc.
15.2.22.TransGene Biotech Co. Ltd.
15.2.23.variantysx
16. Research Methodology 
17. Appendix and Abbreviations 

Key Market Players

  • Agilent Technologies, Inc.
  • Biorad
  • ABM Inc.
  • Cellecta Inc.
  • Charles River laboratories
  • Codex DNA Inc.
  • Creative Biogene
  • Eurofins Scientific
  • EZBioscience
  • GENEWIZ Inc.
  • GenScript
  • Gene2Me
  • iNtRON
  • Jena Bioscience GmbH
  • Lonza
  • Macrogen Inc
  • MerckKGaA
  • New England Biolabs
  • Sartorius AG
  • Takara Bio Inc.
  • Thermo Fisher Scientific Inc.
  • TransGene Biotech Co. Ltd.
  • variantysx

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