Cloning And Mutagenesis Market Size, Share, Growth, Trends, and Global Industry Analysis: By Product Type (Cloning Kits, Mutagenesis Kits, Vectors, and Others), By Gene Type (Standard Gene, Complex Gene), By Technique (Topo PCR Cloning, Blunt End Cloning, Seamless Cloning, Site-Directed Mutagenesis, and Others), By Application (Protein Engineering, Gene Expression, Gene Therapy, Vaccine Research, and Others) And Region

Cloning And Mutagenesis Market size was valued at US$ 2,438.5 million in 2023 and is poised to grow at a CAGR of 19.3% from 2024-2030. Cloning and mutagenesis are fundamental techniques in molecular biology used to manipulate and study genes and DNA sequences. Cloning in molecular biology refers to the process of making identical copies of a DNA sequence, typically a gene or a piece of DNA, and then propagating these copies in a host organism. Mutagenesis involves deliberately inducing mutations in DNA sequences to study gene function. Continuous advancements in genomic technologies, the increasing prevalence of genetic diseases, the rise of personalized medicine, and the acceptance of genetically modified organisms (GMOs) are the main drivers of the market. According to the Canter for Drug Evaluation and Research (CDER), instance for personalized medicine, the Food and Drug Administration approved 37 new molecular entities (NMEs) in 2022. 12 of them were classified as personalized medicines.

Moreover, Ethical considerations regarding genetic manipulation and regulatory frameworks governing the use of genetically modified organisms (GMOs) pose challenges. Additionally, high technical complexity, the need for skilled personnel, and high costs associated with advanced cloning and mutagenesis technologies are also restraints for the market. The COVID-19 pandemic significantly impacted the Cloning and Mutagenesis Market by accelerating the demand for genomic research and sequencing. Cloning and mutagenesis were crucial in the rapid development of COVID-19 vaccines. For instance, the mRNA vaccines by Pfizer-BioNTech and Moderna involved cloning viral genes to produce spike proteins. Increasing adoption of CRISPR/Cas9 systems and growing interest in personalized therapies based on genetic profiles are some of the main opportunities Increasing automation and development of high-throughput cloning and mutagenesis systems, use cases such as bioremediation and sustainable agriculture are considered as main trends

Cloning And Mutagenesis Market Key Developments:

• On February 5, 2024—Takara Bio USA, Inc. launched two critical solutions for oncology research. These automated single-cell total RNA-seq (Shasta Total RNA-Seq Kit) and DNA-seq (Shasta Whole-Genome Amplification Kit) library preparation kits will provide high sample and cell throughput, less hands-on time, and the ability to capture more information than other available technologies.
• In October 2022, iNtRON Biotechnology, a South Korea-based biotech company, introduced its 2nd generation Robot Bacteriophage technology. This technology utilizes random transposon mutagenesis to modify the bacteriophage genome, enabling the identification and removal of non-essential genes.