Cough In Idiopathic Pulmonary Fibrosis Market: By Drug (Pirfenidone, Nintedanib, Interferon gamma-1b, and Others), By Route of Administration (Oral, Parenteral), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and Geography

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The cough in Idiopathic Pulmonary Fibrosis (IPF) market refers to the prevalence, impact, and treatment landscape of cough as a symptom in patients diagnosed with IPF. Idiopathic Pulmonary Fibrosis is a progressive and debilitating lung disease characterized by the scarring of lung tissues, leading to decreased lung function and impaired gas exchange. Among the prominent symptoms experienced by IPF patients, chronic cough is one of the most distressing and persistent manifestations, significantly affecting their quality of life.

According to World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) 2021, it was estimated that IPF affected approximately 3 million people worldwide, with an increasing prevalence in older age groups. The mortality rate of IPF was reported to be around 50,000 to 70,000 deaths annually in the United States alone. Research indicated that up to 80% of IPF patients experience a chronic cough, leading to sleep disturbances, physical limitations, and a reduced ability to perform daily activities. Moreover, cough-related complications, such as fractures, can further deteriorate the patients' health. Treatment options for cough in IPF vary depending on the severity of the symptom and the overall disease progression. Medications like antitussives and corticosteroids are commonly prescribed to manage cough in IPF patients.

However, the limited effectiveness of these treatments underscores the need for novel therapies targeting the underlying mechanisms of IPF and its associated cough. To develop more effective interventions, ongoing research, and clinical trials focus on understanding the pathophysiology of cough in IPF and identifying potential therapeutic targets. The market for IPF treatments is expected to witness significant growth in the coming years, driven by advancements in medical science and the increasing awareness of this rare but devastating condition.

Cough In Idiopathic Pulmonary Fibrosis Market Key Developments:

In July 2022, PureTech, a biotechnology company, announced the initiation of the clinical trial to evaluate the safety and efficacy of LYT-100, (oral drug) as compared to pirfenidone or placebo in adults with Idiopathic Pulmonary Fibrosis. The clinical trial is currently in phase 2 and is actively recruiting.

In September 2020, FibroGen a biotechnology company, announced the initiation of a clinical trial to evaluate the efficacy and safety of 30 milligrams (mg)/kilogram (kg) intravenous (IV) infusions of Pamrevlumab in participants with Idiopathic Pulmonary Fibrosis (IPF). This clinical trial is currently in phase 3 and is actively recruiting.

Cough In Idiopathic Pulmonary Fibrosis Market Summary

Study Period


Base Year




Largest Market

North America

Fastest Growing Market

North America
Cough In Idiopathic Pulmonary Fibrosis Market Dynamics

Cough in idiopathic pulmonary fibrosis (IPF) presents a significant market with various growth drivers and opportunities. Increasing prevalence of IPF globally is expected to drive market growth, as the condition often manifests with persistent, debilitating cough. Moreover, rising awareness among healthcare professionals and patients about the importance of early diagnosis and management of IPF-related cough will create a greater demand for effective treatments. Additionally, ongoing advancements in medical research and technology may lead to the development of novel and more targeted therapies specifically aimed at addressing IPF-associated cough. Furthermore, the growing geriatric population, which is more susceptible to IPF, will contribute to market expansion. Collaborations between pharmaceutical companies and research institutions may also unlock new opportunities for innovative treatments, thereby fueling market growth. Overall, the IPF-related cough market is poised to witness significant development, providing promising prospects for stakeholders in the healthcare sector.

Key Features of the Reports

  • The cough in idiopathic pulmonary fibrosis market report provides granular level information about the market size, regional market share, historic market (2018-2022), and forecast (2023-2029)
  • The report covers in-detail insights about the competitor’s overview, company share analysis, key market developments, and key strategies
  • The report outlines drivers, restraints, unmet needs, and trends that are currently affecting the market
  • The report tracks recent innovations, key developments, and start-up details that are actively working in the market
  • The report provides a plethora of information about market entry strategies, regulatory framework, and reimbursement scenario

Cough In Idiopathic Pulmonary Fibrosis Market Segmentation

By Drug
  •  Pirfenidone
  •  Nintedanib
  •  Interferon gamma-1b
  •  Others
By Route Administration
  • Oral
  • Parenteral
By Distribution Channel
  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Frequently Asked Questions

The Cough In Idiopathic Pulmonary Fibrosis market was valued at USD XX million in 2022 and is expected to grow at XX% CAGR over the forecast period 2023 – 2029.

Key opportunities for the Cough in the Idiopathic Pulmonary Fibrosis market include the development of targeted therapies, innovative diagnostic tools, and increased research investments to address unmet medical needs and improve patient outcomes.

Key trends in the Cough in Idiopathic Pulmonary Fibrosis market include a shift towards personalized treatments, the adoption of telemedicine for remote patient monitoring, and the integration of advanced AI and data analytics in disease management strategies.

Genentech, Inc., Boehringer Ingelheim International GmbH, Avalyn Pharma, Inc., AstraZeneca, Blade Therapeutics, Bristol-Myers Squibb Company, Cipla Inc., F. Hoffmann-La Roche, FibroGen, Inc., Galapagos NV, MediciNova, Inc., Merck & Co., Inc., are a few prominent companies operating in the field of Cough In Idiopathic Pulmonary Fibrosis market.

  • Genentech, Inc.
  • Boehringer Ingelheim International GmbH
  • Avalyn Pharma, Inc.
  • AstraZeneca
  • Blade Therapeutics
  • Bristol-Myers Squibb Company
  • Cipla Inc.
  • Hoffmann-La Roche
  • FibroGen, Inc.
  • Galapagos NV
  • MediciNova, Inc.
  • Merck & Co., Inc.
  • Promedior, Inc.
  • Prometic Life Sciences Inc.
  • Daewoong Pharmaceutical (India) Pvt Ltd
  • Sandoz International GmbH (Novartis)
  • Algernon Pharmaceuticals Inc.

Adjacent Markets